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Polyphenols

Aronia full spectrum - full dose for Aging

N/A

Waitlist Available

Led By Sarah A Johnson, PhD, RDN

Research Sponsored by Colorado State University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline and 6 weeks

Awards & highlights

Study Summary

This trial will assess the efficacy of an aronia berry supplement in improving endothelial function in middle-aged and older adults. The trial will also determine whether the supplement has an effect on the gut microbiota, which may mediate improvements in cardiovascular health.

Eligible Conditions

Endothelial Dysfunction
Aging

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline and 6 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline and 6 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline and 6 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change from baseline reactive hyperemia index (RHI) after 6 weeks consumption

Secondary outcome measures

Augmentation index

Blood ICAM

Blood VCAM

+7 more

Other outcome measures

Fecal polyphenol metabolites

Plasma polyphenol metabolites

Urine polyphenol metabolites

Trial Design

3Treatment groups

Experimental Treatment

Placebo Group

Group I: Aronia full spectrum - half doseExperimental Treatment1 Intervention

Formulation containing 50% Aronia full spectrum and 50% placebo, two capsules once a day, in a 500 mg capsule regimen (total intake 1000 mg)

Group II: Aronia full spectrum - full doseExperimental Treatment1 Intervention

Formulation of 100% Aronia full spectrum, two capsules once a day, in a 500 mg capsule regimen (total intake 1000 mg)

Group III: PlaceboPlacebo Group1 Intervention

Formulation containing inert artificially colored maltodextrin, two capsules once a day, in a 500 mg capsule regimen (total intake 1000 mg)

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Aronia full spectrum - half dose

2019

N/A

~30

Aronia full spectrum - full dose

2019

N/A

~30

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Colorado State UniversityLead Sponsor

125 Previous Clinical Trials

38,335 Total Patients Enrolled

5 Trials studying Aging

131 Patients Enrolled for Aging

Naturex-DbsIndustry Sponsor

5 Previous Clinical Trials

427 Total Patients Enrolled

Sarah A Johnson, PhD, RDNPrincipal InvestigatorDepartment of Food Science and Human Nutrition, Colorado State University

1 Previous Clinical Trials

15 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What qualifications must participants have to join this research trial?

"This clinical research is recruiting 24 patients with endothelial dysfunction that meet the following qualifications: 45-75 years old, BMI between 18.5 and 30 kg/m2, unaltered dietary or exercise habits over the duration of the study (applicable for men and postmenopausal women)."

Answered by AI

Is the recruitment period for this experiment still taking place?

"According to clinicaltrials.gov, the recruitment for this particular trial is inactive at present. This study initially posted on February 11th 2019 and underwent its last edit on August 2nd 2022. Nonetheless, there are currently 284 other trials that are actively searching for participants."

Answered by AI