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TRPV6 Calcium Channel Inhibitor SOR-C13 for Pancreatic Cancer

Phase 1
Waitlist Available
Led By Siqing Fu
Research Sponsored by M.D. Anderson Cancer Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 6 months
Awards & highlights

Study Summary

This trialtests a new drug, SOR-C13, to treat advanced solid tumors. It will measure its side effects and determine the best dose.

Eligible Conditions
  • Pancreatic Cancer
  • Ovarian Cancer
  • Prostate Cancer
  • Solid Tumors
  • Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change of the treatment regimen such as dose delay and dose reduction over time by dose level due to treatment-related adverse events
Dose-limiting toxicities
Incidence of >= grade 2 adverse events according to the National Cancer Institute Common Terminology Criteria for Adverse Events (CTCAE) version 5.0
+2 more
Secondary outcome measures
Clinical benefit
Objective responses
Predictive biomarkers

Trial Design

1Treatment groups
Experimental Treatment
Group I: Treatment (TRPV6 calcium channel inhibitor SOR-C13)Experimental Treatment1 Intervention
Patients receive TRPV6 calcium channel inhibitor SOR-C13 IV over 2 hours on days 1, 2, 8, 9, 15, 16, 22, and 23. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
SOR-C13
Not yet FDA approved

Find a Location

Who is running the clinical trial?

M.D. Anderson Cancer CenterLead Sponsor
2,966 Previous Clinical Trials
1,804,770 Total Patients Enrolled
National Cancer Institute (NCI)NIH
13,654 Previous Clinical Trials
40,933,142 Total Patients Enrolled
Siqing FuPrincipal InvestigatorM.D. Anderson Cancer Center
5 Previous Clinical Trials
531 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there still slots available for volunteers to join this research trial?

"According to clinicaltrials.gov, this clinical trial is in the process of sourcing participants and was first published on July 29th 2019 with its latest update being made on October 20th 2022."

Answered by AI

What is the participant cap for this experiment?

"Affirmative, the facts hosted on clinicaltrials.gov verify that this examination is actively recruiting patients. This experiment was established on July 29th 2019 and most recently modified October 20th 2022. 36 study participants need to be recruited from one research facility."

Answered by AI

What therapeutic uses has SOR-C13, a TRPV6 Calcium Channel Inhibitor, been approved for?

"The TRPV6 Calcium Channel Inhibitor SOR-C13 is a viable therapeutic option for addressing kidney dysfunction, musculoskeletal pain, and osteodystrophy."

Answered by AI

Are there any earlier studies that have used TRPV6 Calcium Channel Inhibitor SOR-C13 as part of their research?

"Presently, 48 clinical trials involving TRPV6 Calcium Channel Inhibitor SOR-C13 are active with 17 in their third phase. Most of these experiments take place near Shanghai; however, 6453 locations worldwide have adopted this research."

Answered by AI

Has the FDA sanctioned SOR-C13, a TRPV6 Calcium Channel Inhibitor?

"SOR-C13, a TRPV6 calcium channel inhibitor, only has limited evidence in regards to safety and efficacy so our team at Power gave it a score of 1."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
A Phase I Study of SOR-C13 in Patients With Advanced Solid Tumors
2019. "A Phase I Study of SOR-C13 in Patients With Advanced Solid Tumors". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03784677.
~2 spots leftby Apr 2025
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