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Preoperative Antibiotics for Dental Implant Failure

Phase 1
Led By Robert Durand, DMD, MS
Research Sponsored by Université de Montréal
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Screening 3 weeks
Treatment Varies
Follow Up 1 week, 4 months, 1 year
Awards & highlights

Study Summary

This trial will study the effect of preoperative azithromycin on implant surgery outcomes. It is a double-masked, placebo-controlled, randomized clinical trial.


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 week, 4 months, 1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 week, 4 months, 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
peri-implant crestal bone change
Secondary outcome measures
bleeding index
duration of surgery (minutes)
+19 more

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: TestActive Control1 Intervention
- 500mg of azithromycin one hour before implant placement
Group II: controlPlacebo Group1 Intervention
- identical placebo one hour before implant placement

Find a Location


Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

Centre de Recherche du Centre Hospitalier de l'Université de MontréalOTHER
51 Previous Clinical Trials
94,237 Total Patients Enrolled
Université de MontréalLead Sponsor
213 Previous Clinical Trials
102,671 Total Patients Enrolled
Robert Durand, DMD, MSPrincipal InvestigatorUniversité de Montréal
1 Previous Clinical Trials
42 Total Patients Enrolled

Media Library

Azithromycin (Antibiotic) Clinical Trial Eligibility Overview. Trial Name: NCT04280406 — Phase 1
Dental Implant Failure Research Study Groups: Test, control
Dental Implant Failure Clinical Trial 2023: Azithromycin Highlights & Side Effects. Trial Name: NCT04280406 — Phase 1
Azithromycin (Antibiotic) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04280406 — Phase 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How does Test impact patients safety?

"Since this is only a Phase 1 trial, meaning that there is limited evidence to support its safety and efficacy, our team at Power rates Test's safety as a 1."

Answered by AI

Are there any open positions for test subjects in this research?

"The trial, which was originally posted on February 25th 2020, is still recruiting patients, as indicated by the most recent update on September 5th 2022."

Answered by AI

What are the common illnesses that Test is used to help alleviate?

"The most popular usage for this medication is the treatment of genital ulcer disease (GUD), however, it can also be used to treat chlamydia in adults, as well as cervicitis."

Answered by AI

Are there any similar investigations to Test that have already been conducted?

"As of right now, there are a total of 54 ongoing studies that are investigating Test. Out of these, 16 are in Phase 3. The majority of the clinical trials for Test are taking place in Albuquerque, New mexico; however, there are a total of 686 locations across the world that are conducting studies on Test."

Answered by AI

How many test subjects are currently a part of this research?

"That is correct. The listing on clinicaltrials.gov indicates that the trial is recruiting patients. This particular study was first posted on February 25th, 2020 and was last updated on September 5th, 2022. They are looking for 50 individuals total from 1 location."

Answered by AI
Recent research and studies
~10 spots leftby Apr 2025