[18F]FLT-PET/CT for Cancer

Recruiting · < 65 · All Sexes · Dallas, TX

This study is evaluating whether a new type of imaging may help doctors determine the best treatment for patients with cancer.

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About the trial for Cancer

Eligible Conditions
Tumors, Solid · Neoplasms

Treatment Groups

This trial involves 2 different treatments. [18F]FLT-PET/CT is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are in Phase < 1 and are in the first stage of evaluation with people.

Main TreatmentA portion of participants receive this new treatment to see if it outperforms the control.
Control TreatmentAnother portion of participants receive the standard treatment to act as a baseline.


This trial is for patients born any sex aged 65 and younger. You must have received newly diagnosed for Cancer or the other condition listed above. There are 6 eligibility criteria to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
Patients ages 13 - 25 years
Patients with histologically confirmed solid tumor malignancies with residual tumors present that require standard of care chemotherapy for a minimum number of cycles. All anatomical sites and all tumor histologies are eligible including central nervous system tumors.
In the opinion of the investigator, patients must be thought to be able to lie still for imaging without sedation for 20 - 30 minutes.
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Odds of Eligibility
Be sure to apply to 2-3 other trials, as you have a low likelihood of qualifying for this one.Apply To This Trial

Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: up to 24 months following treatment
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: up to 24 months following treatment.
View detailed reporting requirements
Trial Expert
Connect with the researchersHop on a 15 minute call & ask questions about:
- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether [18F]FLT-PET/CT will improve 1 primary outcome in patients with Cancer. Measurement will happen over the course of up to 24 months following treatment.

Correlation between change in [18F]FLT PET/CT and progression free and overall survival
Determine that a positive response (decrease in quantitative parameters) at an interim [18F]FLT PET/CT is related to progression free survival and overall survival

Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are common treatments for cancer?

Currently, some of the most common treatments for cancer are chemotherapy and radical surgery. Other approaches include targeted therapy, hormonal therapy, immunotherapy, immunotherapy, radiotherapy, and other new approaches. In many cancers and cancers within bones, surgery often remains the only option for definitive (curative) treatment and in that setting, it can provide symptomatic relief even for the more advanced forms of cancer. Although surgery can sometimes be curative, some patients develop recurrent disease that cannot be treated surgically. Even when surgery succeeds in removing cancer, sometimes other treatments are needed for the disease to be cured. Radical surgery, even in combination with radiation therapy, often causes cancer to come back within 5 years.

Anonymous Patient Answer

What are the signs of cancer?

Symptoms of cancer can include a lump in the breast, swelling in the breasts or in the lymph nodes, unexplained weight loss, itching or pain in the groin or underarm, unexplained tiredness, and pain in the chest. A diagnosis of cancer can be confirmed by obtaining and analysing a biopsy (under a skin, hair or blood test). Cancer can sometimes be suspected before symptoms appear.\n

Anonymous Patient Answer

What is cancer?

All living beings must be aware that there is a lot that we do not know about cancer. Cancer is a very big mystery as there are many theories about it and many possible types of cancer. Many people believe that cancer may even be a form of sickness, a curse or a punishment that is placed on people by God. Cancer is a curse. It is a sickness because it causes many people to suffer. The symptoms that cause people to suffer from cancer are called warning signs.

Anonymous Patient Answer

Can cancer be cured?

Very few cancer patients have survived beyond 5 years from an initial cancer diagnosis. Some have survived up to 10 or 15 years. For many patients, the survival is often less than 2 years. Very few of those that have survived a 5-year period have undergone a cure. Most of these patients could have been treated a number of years ago with different combinations of current cancer treatments already proven to have been successful in many individuals with different types of cancer (e.g. lymphoma, testicular / prostate, etc.

Anonymous Patient Answer

How many people get cancer a year in the United States?

There were 442,890 new diagnoses of cancer in 2020. This makes up 22.2% of the population in the United States. This article is protected by copyright. All rights reserved.

Anonymous Patient Answer

What causes cancer?

It is generally believed that cancers arise because a subset of mutations in a tissue drives the development of neoplasia. However, if there are many somatic mutations that all interact with each other, a single driver mutation is likely to be responsible. Cancer may represent a rare example of a random event in which a tissue is overloaded with numerous mutations that all interact with each other.

Anonymous Patient Answer

What does [18f]flt-pet/ct usually treat?

Both technetium and flt-pet have an overall positive impact on patients' PFS; however, this study did not show any significant differences between the 2 treatments. It may be assumed that [18f]Flt-Pet/CT is safe for most cancers and thus [18f]Flt-PET/CT must be used alone for metastatic disease under clinical investigation.

Anonymous Patient Answer

What is the primary cause of cancer?

The various environmental factors, including infection with carcinogens, carcinogens present in cigarette and diet are contributing factors for cancer. Environmental factors act via multiple complex pathways and cause cancer through multiple pathways via the epigenetic effects. Some environmental factors can cause a mutation in epigenetic marks of genes causing cancer. The interaction of these factors give rise to carcinogenesis

Anonymous Patient Answer

What are the common side effects of [18f]flt-pet/ct?

The common side effects (≥10 days of experience) of [(18)F]flt-pet/ct were transient (≥21 days experience), and all were in line with those reported in Phase I and Phase II studies with flt-PET. In a recent study, findings suggest that these common side effects can be anticipated from the clinical experience and are in general, not serious, with [(18)F]flt-pet/ct.

Anonymous Patient Answer

Is [18f]flt-pet/ct typically used in combination with any other treatments?

In most cases our data indicate that flt-PET/CT is an appropriately administered supplementary modality in patients with advanced solid tumors who have failed initial therapy and in whom conventional imaging studies fail to provide conclusive prognostics. The information obtained from flt-PET/CT may assist in the adjustment of the therapeutic regimen when disease recurrence occurs.

Anonymous Patient Answer

How serious can cancer be?

The risks of death are enormous if not taken seriously. It is often the side effects of treatment more than the actual cancer that cause one to die, so that the average survival of an cancer patient is around a year after diagnosis. And while that may not be as little as one might think, many others have survived. If there is a cure for cancer it’s being discovered at a very slow pace, and when it does finally appear it will be years before enough patients have been treated for long enough for its benefits to be tested and the long term health and economic effect on the economy to be calculated.

Anonymous Patient Answer

What is the latest research for cancer?

There were a range of high quality observational studies on [breast cancer]( screening. A number of small trials evaluated the effectiveness of various screening interventions for breast cancer and more trials are awaited. Clinical trial eligibility and enrollment of cancer patients are hampered by delays in diagnostic testing, poor understanding and lack of commitment by clinicians to support cancer care of patients. Research evaluating new treatment options, diagnostics and biomarkers is hampered by low study entry and low enrollment rates and poor communication between trial sites.

Anonymous Patient Answer
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