← Back to Search

Cyclin-Dependent Kinase Inhibitor

Up to 8 subjects will be enrolled and studied as a single group for Healthy Subjects

Q: Is this research endeavor restricted to persons aged 20 or above?

According to the inclusion criteria, those wishing to participate in this study must be between 18 and 55 years old. There are additional trials for individuals under 18 (56 studies) as well as a larger number of research opportunities available for people over 65 (367 studies).

Q: To what criteria do patients have to adhere in order to participate in this research?

This clinical trial is currently seeking 8 healthy participants aged between 18 and 55. Furthermore, male candidates must commit to contraception use, while <a href="https://www.withpower.com/clinical-trials/all">all</a> applicants must have at least one bowel movement per day in their medical history.

Q: Is this venture currently open to new participants?

Per the information found on clinicaltrials.gov, no new participants are being recruited for this medical trial at present. The study was initially posted in March of 2023 and has not been updated since April 5th of that same year. Despite this particular trial's lack of recruitment opportunities, 812 other trials remain open to applicants presently.

Phase < 1

Waitlist Available

Research Sponsored by Cyclacel Pharmaceuticals, Inc.

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to day 15

Awards & highlights

Study Summary

This trial will study how a drug is absorbed, broken down, and excreted in healthy men.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to day 15

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to day 15

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to day 15 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

AUC for CYC065 in plasma

Cmax for CYC065 in plasma

The routes, rates of elimination, and mass balance

+2 more

Secondary outcome measures

Concentration of CYC065 metabolites

Incidence and severity of AEs

Trial Design

1Treatment groups

Experimental Treatment

Group I: Up to 8 subjects will be enrolled and studied as a single groupExperimental Treatment1 Intervention

The purpose of this study is to determine the absorption, metabolism, and excretion (AME) of [14C]CYC065 and to characterize and determine, where possible, the metabolites present in plasma, urine, and feces in healthy male subjects following a single oral administration.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Cyclacel Pharmaceuticals, Inc.Lead Sponsor

19 Previous Clinical Trials

2,471 Total Patients Enrolled

Mark H Kirschbaum, MDStudy ChairCyclacel Pharmaceuticals, Inc.

1 Previous Clinical Trials

330 Total Patients Enrolled

Media Library

Fadraciclib (Cyclin-Dependent Kinase Inhibitor) Clinical Trial Eligibility Overview. Trial Name: NCT05817890 — Phase < 1

Healthy Subjects Research Study Groups: Up to 8 subjects will be enrolled and studied as a single group

Healthy Subjects Clinical Trial 2023: Fadraciclib Highlights & Side Effects. Trial Name: NCT05817890 — Phase < 1

Fadraciclib (Cyclin-Dependent Kinase Inhibitor) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05817890 — Phase < 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this research endeavor restricted to persons aged 20 or above?

"According to the inclusion criteria, those wishing to participate in this study must be between 18 and 55 years old. There are additional trials for individuals under 18 (56 studies) as well as a larger number of research opportunities available for people over 65 (367 studies)."

Answered by AI

To what criteria do patients have to adhere in order to participate in this research?

"This clinical trial is currently seeking 8 healthy participants aged between 18 and 55. Furthermore, male candidates must commit to contraception use, while all applicants must have at least one bowel movement per day in their medical history."

Answered by AI

Is this venture currently open to new participants?

"Per the information found on clinicaltrials.gov, no new participants are being recruited for this medical trial at present. The study was initially posted in March of 2023 and has not been updated since April 5th of that same year. Despite this particular trial's lack of recruitment opportunities, 812 other trials remain open to applicants presently."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Absorption, Metabolism, and Excretion of CYC065 in Healthy Male Subjects

2023. "Absorption, Metabolism, and Excretion of CYC065 in Healthy Male Subjects". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05817890.