All > Recurrent Glioblastoma > Oligodendroglioma

Microdevice for Glioblastoma

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Brigham and Women's Hospital, Boston, MAGlioblastoma+7 MoreMicrodevice - CombinationProduct
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial will test the safety and feasibility of using a microdevice to measure local response to chemotherapy and other drugs in brain tumors.

Eligible Conditions
  • Glioblastoma
  • Astrocytoma
  • Grade II Brain Tumor
  • Oligodendroglioma
  • Anaplastic Oligodendroglioma
  • Anaplastic Astrocytoma
  • Grade III Brain Tumor

Treatment Effectiveness

Effectiveness Progress

1 of 3

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barzolvolimab

Study Objectives

2 Primary · 2 Secondary · Reporting Duration: 1 Day

1 Day
Correlate Tissue Genetic Features with Drug Response
Measure Local Intratumor Response to Different Agents
Number of Participants with Microdevice Related Adverse Events as Assessed by CTCAE Volume 5.0
1 day
Success Rate of Microdevice Retrieval

Trial Safety

Safety Progress

1 of 3

Similar Trials

1
Palbociclib
1
ABBV-514
2
barzolvolimab

Trial Design

1 Treatment Group

Microdevice
1 of 1

Experimental Treatment

12 Total Participants · 1 Treatment Group

Primary Treatment: Microdevice · No Placebo Group · Phase < 1

Microdevice
CombinationProduct
Experimental Group · 1 Intervention: Microdevice · Intervention Types: CombinationProduct

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 1 day

Who is running the clinical trial?

Oliver Jonas, PhDLead Sponsor
Oliver JonasLead Sponsor
1 Previous Clinical Trials
5 Total Patients Enrolled
Pier Paolo Peruzzi, MD, PhDPrincipal InvestigatorBrigham and Women's Hospital

Eligibility Criteria

Age 18+ · All Participants · 9 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
Since the study drugs will only be given for a short time in a specific area, it is unlikely that they will interact with any other medication you are taking. Therefore, you can still participate in the study if you are taking medications that affect CYP450 enzymes.
References

Frequently Asked Questions

What is the present size of this trial's participant pool?

"Affirmative. According to clinicaltrials.gov, this medical experiment has been actively recruiting since it was first posted on March 3rd 2020 and last modified on February 26th 2023. It seeks out 12 participants at one particular site." - Anonymous Online Contributor

Unverified Answer

Are there any empty slots left in this experiment for volunteers?

"According to clinicaltrials.gov, this study is actively enrolling participants. It was initially advertised on March 3rd 2020 and the most recent update occurred on February 26th 2023." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

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