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Small Molecule Inhibitor

AMG 337 for Clear Cell Sarcoma of Soft Tissue

Phase 2
Waitlist Available
Research Sponsored by NantPharma, LLC
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 year
Awards & highlights

Study Summary

This trial will study if a new drug, AMG 337, can shrink tumors in people with advanced clear cell sarcoma that contains a specific gene fusion.

Eligible Conditions
  • Clear Cell Sarcoma of Soft Tissue

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Objective Response Rate (ORR)
Secondary outcome measures
Disease Control Rate (DCR)
Duration of Response (DOR)
Incidence of Treatment-Emergent Adverse Events (Safety And Tolerability)
+2 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: AMG 337Experimental Treatment1 Intervention
AMG 337 will be administered in patients with advanced or metastatic clear cell sarcoma
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
AMG 337
2014
Completed Phase 2
~130

Find a Location

Who is running the clinical trial?

NantPharma, LLCLead Sponsor
2 Previous Clinical Trials

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
QUILT-3.031: AMG 337 in Subjects With Advanced or Metastatic Clear Cell Sarcoma
2018. "QUILT-3.031: AMG 337 in Subjects With Advanced or Metastatic Clear Cell Sarcoma". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03132155.
~1 spots leftby Apr 2025
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