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Texas Children's Hospital

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Houston, Texas 77030
Global Leader in Syndrome
Global Leader in Lymphoma
Conducts research for Brain Tumor
Conducts research for Leukemia
Conducts research for Tumors
782 reported clinical trials
117 medical researchers
Photo of Texas Children's Hospital in HoustonPhoto of Texas Children's Hospital in Houston

Summary

Texas Children's Hospital is a medical facility located in Houston, Texas. This center is recognized for care of Syndrome, Lymphoma, Brain Tumor, Leukemia, Tumors and other specialties. Texas Children's Hospital is involved with conducting 782 clinical trials across 950 conditions. There are 117 research doctors associated with this hospital, such as Jennifer Foster, MD, Patricia Baxter, MD, Rayne H. Rouce, and Carlos Ramos, MD.

Area of expertise

1Syndrome
Global Leader
Texas Children's Hospital has run 54 trials for Syndrome. Some of their research focus areas include:
COL3A1 positive
MECP2 positive
FBN1 positive
2Lymphoma
Global Leader
Texas Children's Hospital has run 47 trials for Lymphoma. Some of their research focus areas include:
CD30 positive
EBV positive
Stage IV

Top PIs

Clinical Trials running at Texas Children's Hospital

Brain Tumor
Acute Myeloid Leukemia
Craniopharyngioma
Diffuse Intrinsic Pontine Glioma
Crohn's Disease
Medulloblastoma
Leukemia
Hemophagocytic Lymphohistiocytosis
Oligodendroglioma
Tumors
Image of trial facility.

Dabrafenib + Trametinib

for Brain Tumors

This study is evaluating whether a combination of two drugs may help children with cancer.
Recruiting3 awards Phase 47 criteria
Image of trial facility.

DAY101 vs. Chemotherapy

for Pediatric Brain Cancer

This is a 2-arm, randomized, open-label, multicenter, global, Phase 3 trial to evaluate the efficacy, safety, and tolerability of tovorafenib monotherapy versus standard of care (SoC) chemotherapy in patients with pediatric low-grade glioma (LGG) harboring an activating rapidly accelerated fibrosarcoma (RAF) alteration requiring front-line systemic therapy.
Recruiting2 awards Phase 3
Image of trial facility.

SurVaxM Vaccine

for Brain Cancer

Patients will receive a vaccine called SurVaxM on this study. While vaccines are usually thought of as ways to prevent diseases, vaccines can also be used to treat cancer. SurVaxM is designed to tell the body's immune system to look for tumor cells that express a protein called survivin and destroy them. The survivin protein can be found on up to 95% of glioblastomas and other types of cancer but is not found in normal cells. If the body's immune system knows to destroy cells that express survivin, it may help to control tumor growth and recurrence. SurVaxM will be mixed with Montanide ISA 51 before it is given. Montanide ISA 51 is an ingredient that helps create a stronger immune response in people, which helps the vaccine work better. This study has two phases: Priming and Maintenance. During the Priming Phase, patients will get one dose of SurVaxM combined with Montanide ISA 51 through a subcutaneous injection (a shot under the skin) at the start of the study and every 2 weeks for 6 weeks (for a total of 4 doses). At the same time that patients get the SurVaxM/Montanide ISA 51 injection, they will also get a second subcutaneous injection of a medicine called sargramostim. Sargramostim is given close to the SurVaxM//Montanide ISA 51 injection and works to stimulate the immune system to help the SurVaxM/Montanide ISA 51 work more effectively. If a patient completes the Priming Phase without severe side effects and his or her disease stays the same or improves, he or she can continue to the Maintenance Phase. During the Maintenance Phase, the patient will get a SurVaxM/Montanide ISA 51 dose along with a sargramostim dose about every 8 weeks for up to two years. After a patient finishes the study treatment, the doctor and study team will continue to follow his/her condition and watch for side effects up to 3 years following the last dose of SurVaxM/Montanide ISA 51. Patients will be seen in clinic every 3 months during the follow-up period.
Recruiting1 award Phase 1

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Frequently asked questions

What kind of research happens at Texas Children's Hospital?
Texas Children's Hospital is a medical facility located in Houston, Texas. This center is recognized for care of Syndrome, Lymphoma, Brain Tumor, Leukemia, Tumors and other specialties. Texas Children's Hospital is involved with conducting 782 clinical trials across 950 conditions. There are 117 research doctors associated with this hospital, such as Jennifer Foster, MD, Patricia Baxter, MD, Rayne H. Rouce, and Carlos Ramos, MD.
Where is Texas Children's Hospital located?
**Directions to Texas Children's Hospital, Houston:** - For direct access, take I-69 to Fannin St and proceed south. - For real-time navigation, use the Waze app and enter the address: 6621 Fannin St.
Who should I call to ask about financial aid or insurance network?
### Texas Children's Hospital Contact Information **Financial Assistance and Insurance Departments:** - **Hospital Billing Office:** 832-824-2300 - **Texas Children's Health Plan Member Services:** - **CHIP:** 832-828-1002 (Local), 1-866-959-6555 (Toll-Free), TTY 800-735-2989 - **STAR:** 832-828-1001 (Local), 1-866-959-2555 (Toll-Free), TTY 800-735-2989 - **STAR Kids:** 832-828-1003 (Local), 1-800-659-5764 (Toll-Free), TTY 800-735-2989 **Appeals Department:** - **Address:** Texas Children’s Health Plan Attention: Appeals Department NB8390, PO Box 300709, Houston, TX 77230 - **Fax:** 832-825-8796 - **Phone:** 832-828-1001 or 1-866-959-2555, TTY/TDD: 1-800-735-2989 ### UT Southwestern Medical Center Contact Information **Financial Assistance:** - **Phone:** 469-291-2000 or 866-648-2455 - **Address:** Financial Assistance, P.O. Box 36423, Dallas, Texas 75235-9662
What insurance does Texas Children's Hospital accept?
Texas Children's Hospital accepts a wide range of insurance plans, including but not limited to Aetna HMO, Aetna POS, Aetna PPO, BCBS BlueChoice PPO/EPO, BCBS Blue Essentials, BCBS Par Plan, and Choice Care Network PPO (Humana). Additionally, Texas Children's Health Plan provides no-cost health coverage for eligible children and young adults under 21 with disabilities. For the most current information on accepted insurance plans, contacting the hospital directly is advised.
What awards or recognition has Texas Children's Hospital received?
Texas Children's Hospital in Houston, Texas, is renowned for its pediatric cancer care, ranking among the nation's best by U.S. News & World Report. It boasts over 250 active therapeutic clinical trials and receives $40 million in annual research funding. The Jan and Dan Duncan Neurological Research Institute focuses on pediatric and adult brain disorders, with over 25 principal investigators and 200 scientists.