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Houston Methodist Hospital

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Houston, Texas 77030

Global Leader in Stroke

Global Leader in Breast Cancer

Conducts research for Lung Cancer

Conducts research for Heart Failure

Conducts research for Mixed-Cell Lymphoma

821 reported clinical trials

101 medical researchers

Photo of Houston Methodist Hospital in HoustonPhoto of Houston Methodist Hospital in HoustonPhoto of Houston Methodist Hospital in Houston

Summary

Houston Methodist Hospital is a medical facility located in Houston, Texas. This center is recognized for care of Stroke, Breast Cancer, Lung Cancer, Heart Failure, Mixed-Cell Lymphoma and other specialties. Houston Methodist Hospital is involved with conducting 821 clinical trials across 1,021 conditions. There are 101 research doctors associated with this hospital, such as Jun Zhang, Carlos Ramos, MD, Maen Abdelrahim, MD, and Rayne H. Rouce.

Area of expertise

1

Stroke

Global Leader

Houston Methodist Hospital has run 44 trials for Stroke.

2

Breast Cancer

Global Leader

Houston Methodist Hospital has run 44 trials for Breast Cancer. Some of their research focus areas include:

Stage IV
HER2 positive
HER2 negative

Top PIs

Clinical Trials running at Houston Methodist Hospital

Lung Cancer

Ovarian Cancer

Prostate Cancer

Multiple Myeloma

Breast Cancer

Bladder Cancer

Uterine Cancer

Pancreatic Cancer

Fallopian Tube Cancer

Non-Small Cell Lung Cancer

Image of trial facility.

Crizotinib

for Non-Small Cell Lung Cancer

This randomized phase III trial studies how well crizotinib works in treating patients with stage IB-IIIA non-small cell lung cancer that has been removed by surgery and has a mutation in a protein called anaplastic lymphoma kinase (ALK). Mutations, or changes, in ALK can make it very active and important for tumor cell growth and progression. Crizotinib may stop the growth of tumor cells by blocking the ALK protein from working. Crizotinib may be an effective treatment for patients with non-small cell lung cancer and an ALK fusion mutation.

Recruiting

2 awards

Phase 3

28 criteria

Image of trial facility.

Osimertinib + Bevacizumab

for Lung Cancer

This phase III trial compares the effect of bevacizumab and osimertinib combination vs. osimertinib alone for the treatment of non-small cell lung cancer that has spread outside of the lungs (stage IIIB-IV) and has a change (mutation) in a gene called EGFR. The EGFR protein is involved in cell signaling pathways that control cell division and survival. Sometimes, mutations in the EGFR gene cause EGFR proteins to be made in higher than normal amounts on some types of cancer cells. This causes cancer cells to divide more rapidly. Osimertinib may stop the growth of tumor cells by blocking EGFR that is needed for cell growth in this type of cancer. Bevacizumab is in a class of medications called antiangiogenic agents. It works by stopping the formation of blood vessels that bring oxygen and nutrients to tumor. This may slow the growth and spread of tumor. Giving osimertinib with bevacizumab may control cancer for longer and help patients live longer as compared to osimertinib alone.

Recruiting

2 awards

Phase 3

31 criteria

Image of trial facility.

Immunotherapy + Chemotherapy

for Non-Small Cell Lung Cancer

This phase III ALCHEMIST treatment trial tests the addition of pembrolizumab to usual chemotherapy for the treatment of stage IIA, IIB, IIIA or IIIB non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Chemotherapy drugs, such as cisplatin, pemetrexed, carboplatin, gemcitabine hydrochloride, and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving pembrolizumab with usual chemotherapy may help increase survival times in patients with stage IIA, IIB, IIIA or IIIB non-small cell lung cancer.

Recruiting

2 awards

Phase 3

27 criteria

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Unbiased Results

We believe in providing patients with all the options.

Your Data Stays Your Data

We only share your information with the clinical trials you're trying to access.

Verified Trials Only

All of our trials are run by licensed doctors, researchers, and healthcare companies.

Terms of Service·Privacy Policy·Cookies·Security

Unbiased Results

We believe in providing patients with all the options.

Your Data Stays Your Data

We only share your information with the clinical trials you're trying to access.

Verified Trials Only

All of our trials are run by licensed doctors, researchers, and healthcare companies.

Terms of Service·Privacy Policy·Cookies·Security