← Back to Search

Fully Integrated Treatment for Alcoholism (FIT Trial)

N/A
Waitlist Available
Led By Kate Wolitzky-Taylor, PhD
Research Sponsored by University of California, Los Angeles
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 3 months, and 6 months
Awards & highlights

FIT Trial Summary

Alcohol use disorders (AUD) and social anxiety disorder (SAD) are highly comorbid and associated with significant impairment. Social anxiety comorbidity is associated with poorer addiction treatment engagement and outcomes. Thus, addressing underlying SAD symptoms that may lead to and maintain alcohol problems, as well as undermine successful treatment for AUD, is warranted. This proposal aims to develop and evaluate a fully integrated outpatient program for comorbid SAD and AUD that weaves evidence-based treatment for SAD (i.e., exposure-based cognitive behavioral therapy) into a traditional, evidence-based treatment for AUD. First, the investigators will develop the protocol for the fully integrated treatment (FIT). The overarching goal of FIT will be to simultaneously deliver AUD and SAD treatment. Development will be an iterative process guided by previous research (including our own), and by input from clinicians, administrators, and patients in an outpatient substance use disorder treatment clinic. After the protocol is developed, the investigators will use their established clinician training procedures to train clinicians at their community partnered clinic to competently deliver the intervention. After protocol development and clinician training, the investigators will conduct a pilot randomized clinical trial (RCT) comparing the efficacy of our fully integrated treatment (FIT) for comorbid alcohol use and social anxiety disorders to usual care (UC) in the community substance use disorder specialty clinic. The goals of the RCT will be to gather data regarding acceptability, feasibility, and preliminary efficacy of the FIT protocol. The investigators will randomize treatment-seeking participants (N = 60) who have comorbid SAD and AUD. The investigators will assess treatment engagement, social anxiety outcomes, and alcohol use outcomes at baseline, 3-months, and 6-months from baseline. The investigators will also gather qualitative and quantitative acceptability data from patients after completing FIT, which may guide final refinements of FIT prior to testing in a larger-scale grant. The knowledge gained from this investigation has the potential to significantly improve the treatment of alcohol use disorders and make a significant public health impact. The focus on direct translation to community practice paradigms and the emphasis on full mental health and addiction treatment integration significantly advance the field.

Eligible Conditions
  • Alcoholism
  • Social Anxiety Disorder

FIT Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 3 months, and 6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 3 months, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Ethanol
Change from Baseline Social Anxiety Symptoms in Situations at 3 and 6 months
Secondary outcome measures
Change from Baseline Alcohol Abstinence at 3 and 6 months
Change from Baseline Alcohol Drinks per Day at 3 and 6 months
Change from Baseline Alcohol Problems at 3 and 6 months
+4 more

FIT Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Fully Integrated TreatmentExperimental Treatment1 Intervention
Evidence-based substance use treatment combined with Cognitive Behavioral Therapy (CBT) for Social Anxiety Disorder Intervention name: Fully integrated treatment
Group II: Usual Intensive Outpatient CareActive Control1 Intervention
Evidence-based substance use disorder treatment Intervention name: Stand-alone Intensive Outpatient Program
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Fully integrated treatment
2018
N/A
~60

Find a Location

Who is running the clinical trial?

University of California, Los AngelesLead Sponsor
1,532 Previous Clinical Trials
10,265,212 Total Patients Enrolled
16 Trials studying Alcoholism
3,730 Patients Enrolled for Alcoholism
National Institute on Alcohol Abuse and Alcoholism (NIAAA)NIH
802 Previous Clinical Trials
1,365,389 Total Patients Enrolled
424 Trials studying Alcoholism
985,812 Patients Enrolled for Alcoholism
Matrix Institute on AddictionsUNKNOWN

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
~8 spots leftby Apr 2025