Sugar Reduction Program for Preventing Obesity
(MAMITA Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
The purpose of this study is to determine whether a health education program incorporating sugar sweetened beverage and juice (SSB/J) reduction and home water delivery affects maternal and infant risk for obesity by randomizing mother-infant dyads to one of three 24-month interventions: Group 1 (control): standard health education program only; Group 2 (translation): health education program focused on sugar reduction; and Group 3 (efficacy): health education program focused on sugar reduction and bottled water delivery. The intervention program will be delivered by trained health educators during in-person home visits, or virtually via phone or video calls.
Will I have to stop taking my current medications?
The trial excludes participants who are on chronic medications that affect body weight, insulin resistance, or lipid profiles, so you may need to stop such medications to participate.
Is the Sugar Reduction Program for Preventing Obesity safe for humans?
The Sugar Reduction Program, evaluated in various studies, appears to be safe for humans. In a study with Latino youth, reducing sugar intake did not cause any harmful effects and was associated with some health improvements. Another study showed that nutrition education programs, which may include sugar reduction, can positively impact health without adverse effects.12345
How does the Sugar Reduction Program for Preventing Obesity differ from other treatments for obesity?
The Sugar Reduction Program is unique because it focuses specifically on reducing sugar intake through health education, unlike other programs that may emphasize general weight loss strategies or physical activity. This targeted approach aims to prevent obesity by addressing one of its key dietary contributors.45678
What data supports the effectiveness of the Sugar Reduction Program for Preventing Obesity treatment?
Research shows that behavior modification and nutrition education, similar to the components of the Sugar Reduction Program, have been effective in helping children lose weight in school-based programs. Additionally, self-regulation techniques in dietary control have led to significant weight loss in adults, suggesting that structured programs focusing on behavior change and education can be effective in preventing obesity.49101112
Who Is on the Research Team?
Michael I Goran
Principal Investigator
University of Southern California; Children's Hospital Los Angeles
Are You a Good Fit for This Trial?
This trial is for mothers who often drink sugary beverages and juices, can understand study procedures in English or Spanish at a 5th grade level, have had a single birth up to one month postpartum, and identify as Hispanic. It excludes those with major illnesses like diabetes, on weight-affecting meds, smokers or drug users, with pre-term infants or fetal abnormalities.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Intervention
Participants receive a health education program focused on sugar reduction and home bottled water delivery
Follow-up
Participants are monitored for changes in maternal and infant weight, diet, and other health metrics
What Are the Treatments Tested in This Trial?
Interventions
- Control health education program
- Home water delivery
- Sugar reduction health education program
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Southern California
Lead Sponsor
Children's Hospital Los Angeles
Collaborator