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Procedure

Radiofrequency Energy Applications for Atrial Fibrillation (REACT Trial)

N/A
Waitlist Available
Research Sponsored by Texas Cardiac Arrhythmia Research Foundation
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1-3 months
Awards & highlights

REACT Trial Summary

This trial is evaluating the safety and efficacy of using radiofrequency energy to close a leak in the left atrial appendage. The left atrial appendage is a small sac in the heart that can sometimes leak and cause blood stagnation and thrombus formation, which can lead to a thromboembolic event.

Eligible Conditions
  • Atrial Fibrillation
  • Left Atrial Appendage Thrombosis
  • Ischemic Stroke

REACT Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1-3 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1-3 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Procedural Success
Secondary outcome measures
Peri-Procedural Success

REACT Trial Design

1Treatment groups
Experimental Treatment
Group I: RF EnergyExperimental Treatment1 Intervention
RF delivery targeting the atrial side of a significant residual leak in patients with acute and chronic evidence of incomplete percutaneous LAA occlusion

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Who is running the clinical trial?

Texas Cardiac Arrhythmia Research FoundationLead Sponsor
37 Previous Clinical Trials
13,280 Total Patients Enrolled
26 Trials studying Atrial Fibrillation
6,545 Patients Enrolled for Atrial Fibrillation

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are new participants being accepted for this research study currently?

"This research, initially posted on February 1st 2021 and then revised a week later, is not recruiting patients currently. Nevertheless, other 939 studies are welcoming participants at this time."

Answered by AI
Recent research and studies
JACC: Clinical ElectrophysiologyJournal
Radiofrequency Energy Applications Targeting Significant Residual Leaks After Watchman Implantation
Della Rocca, Domenico G., Ghulam Murtaza, Luigi Di Biase, Krishna Akella, Subramaniam C. Krishnan, Michele Magnocavallo, Sanghamitra Mohanty, et al.. 2021. “Radiofrequency Energy Applications Targeting Significant Residual Leaks After Watchman Implantation”. JACC: Clinical Electrophysiology. Elsevier BV. doi:10.1016/j.jacep.2021.06.002.
JACC: Clinical ElectrophysiologyJournal
Radiofrequency Energy Applications Targeting Significant Residual Leaks After Watchman Implantation
Della Rocca, Domenico G., Ghulam Murtaza, Luigi Di Biase, Krishna Akella, Subramaniam C. Krishnan, Michele Magnocavallo, Sanghamitra Mohanty, et al.. 2021. “Radiofrequency Energy Applications Targeting Significant Residual Leaks After Watchman Implantation”. JACC: Clinical Electrophysiology. Elsevier BV. doi:10.1016/j.jacep.2021.06.002.
clinicaltrials.govStudy
RF Applications for Residual LAA Leaks
Andrea Natale 2021. "RF Applications for Residual LAA Leaks". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04726943.
~24 spots leftby Apr 2025
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