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NB Medication for Weight Management After Bariatric Surgery
Study Summary
This trial will test whether naltrexone/bupropion can help people who have bariatric surgery to maintain weight loss and control their eating.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I started losing control over eating 6 months post-bariatric surgery and responded well to a 4-month treatment.You have a history of eating disorders such as anorexia or bulimia.You have a mental health condition that requires hospitalization or intensive treatment, such as bipolar disorder, psychosis, or severe depression.I have gallbladder disease.I have a severe kidney, liver, nerve, lung disease, or another serious health issue.My diabetes is not currently under control.I am currently receiving treatment for an eating disorder or to lose weight.I have a history or risk of seizures due to various conditions or treatments.My blood pressure or heart rate is higher than normal and untreated.I have a history of heart or blood vessel diseases, including stroke.You have thoughts of hurting yourself or others.It has been about 10 months since my surgery.I am currently taking medication to lose weight.You are allergic or sensitive to bupropion or naltrexone.My high blood pressure is not under control.I have struggled with drug or alcohol dependence after my weight loss surgery.I am between 18 and 70 years old.I have had weight loss surgery.I am not on medications like MAOIs or opiates that conflict with NB medication.
- Group 1: Naltrexone+Bupropion Medication
- Group 2: Placebo
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are people with the required medical conditions able to join this trial at this time?
"This particular trial is not currently enrolling new participants, as it was last updated on October 4th, 2022. You may be interested in other trials concerning overweight individuals or those taking Naltrexone and Bupropion (NB) medication, of which there are presently 346 and 71 clinical trials respectively."
Are there specific types of people who would be more likely to benefit from this trial?
"To qualify for this research, applicants must be overweight and between 18-70 years old. Up to one hundred individuals will be accepted into the trial."
Is this clinical trial open to people who are under 40 years old?
"The age requirements for this study state that all participants must be over 18 and cannot be older than 70."
What are the usual medical conditions that Naltrexone and Bupropion (NB) are employed to help alleviate?
"The NB medication, which is a combination of naltrexone and bupropion, can be used to treat conditions like attention deficit hyperactivity disorder (ADHD), seasonal affective disorder, and smoking cessation."
How many test subjects are included in this experiment?
"As of right now, this clinical trial is not trying to recruit patients. The study was first posted on January 10th, 2022 and was edited October 4th, 2022. If you are looking for other studies, there are currently 346 trials actively enrolling patients with overweight and 71 trials for Naltrexone and Bupropion (NB) medication that need participants."
Who else is applying?
What state do they live in?
How old are they?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How responsive is this trial?
Typically responds via
Most responsive sites:
- Yale School of Medicine: < 48 hours
Average response time
- < 2 Days
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