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Physical Activity for Alzheimer's Disease (RAATE-MCI Trial)

N/A

Recruiting

Led By Robert L Newton, Jr., PhD

Research Sponsored by Pennington Biomedical Research Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Have a Short Physical Performance Battery score ≥4

Aged 60 and older

Timeline

Screening 3 weeks

Treatment Varies

Follow Up sv, 26 weeks, 52 weeks

Awards & highlights

RAATE-MCI Trial Summary

This trial will compare the effects of physical activity on risk factors for Alzheimer's Disease in older African American adults.

Who is the study for?

The RAATE-MCI trial is for African American adults aged 60 or older who self-identify as such, are willing to be randomly assigned to groups, can attend sessions and travel within the study area for a year. They must be physically able to exercise but not currently active, have mild cognitive impairment without severe dementia, and agree to data use after the study.Check my eligibility

What is being tested?

This trial tests if physical activity affects Alzheimer's risk factors in older African Americans. Participants will either join a physical activity program or an active control group for one year. The goal is to see how exercise influences cognitive health compared with usual activities.See study design

What are the potential side effects?

Since this trial involves a physical activity program, potential side effects may include typical exercise-related risks like muscle soreness, strains or sprains. However, participants deemed at risk for serious exercise-related issues by medical staff won't be included.

RAATE-MCI Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

My physical ability score is 4 or higher.

Select...

I am 60 years old or older.

RAATE-MCI Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ sv, 26 weeks, 52 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~sv, 26 weeks, 52 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and sv, 26 weeks, 52 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in episodic memory

Change in executive function

Secondary outcome measures

APOE genotype

Change in brain structure

Change in cardiorespiratory fitness

+14 more

RAATE-MCI Trial Design

2Treatment groups

Experimental Treatment

Group I: Successful AgingExperimental Treatment1 Intervention

Low intensity activity program and a healthy aging educational component

Group II: Physical ActivityExperimental Treatment1 Intervention

150 minutes of physical activity weekly

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Successful Aging

2019

Completed Phase 3

~1720

Physical activity program

2007

N/A

~300

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Pennington Biomedical Research CenterLead Sponsor

304 Previous Clinical Trials

181,292 Total Patients Enrolled

National Institute on Aging (NIA)NIH

1,669 Previous Clinical Trials

28,004,970 Total Patients Enrolled

Robert L Newton, Jr., PhDPrincipal InvestigatorPennington Biomedical Research

2 Previous Clinical Trials

222 Total Patients Enrolled

Media Library

Physical activity program Clinical Trial Eligibility Overview. Trial Name: NCT04956549 — N/A

Alzheimer's Dementia Research Study Groups: Physical Activity, Successful Aging

Alzheimer's Dementia Clinical Trial 2023: Physical activity program Highlights & Side Effects. Trial Name: NCT04956549 — N/A

Physical activity program 2023 Treatment Timeline for Medical Study. Trial Name: NCT04956549 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What type of individuals is this trial targeting?

"This clinical trial has a narrow enrolment window, with only those aged between 60 and 85 being eligible to participate. In total, 144 patients are expected to take part in the study."

Answered by AI

What is the desired outcome of this trial?

"This experiment, which entails monitoring participants over the course of a Baseline, 24 weeks and 52 week timeline, has ascertained episodic memory as its primary goal. Supplementary objectives involve tracking changes in physical function-SPPB (Short Physical Performance Battery), lipoproteins and glucose levels by assessing fasting concentrations with standard assays."

Answered by AI

What is the uppermost capacity of participants for this experiment?

"Affirmative. According to the information listed on clinicaltrials.gov, this medical trial is in its recruitment phase and was first posted on June 1st 2021. The latest update occurred February 15th 2022 and 144 participants are needed from a single location."

Answered by AI

Are senior citizens within the eligible age range for participating in this experiment?

"As indicated in the eligibility requirements of this trial, elderly participants aged between 60 and 85 inclusive are welcome to enroll."

Answered by AI

Is there an opportunity for recruitment in this clinical trial?

"Affirmative. According to information located on the clinicaltrials.gov website, this research endeavour is still actively seeking volunteers, having been initially published on June 1st 2021 and last amended on February 15th 2022. The trial aims to recruit a total of 144 participants from one location."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Reducing African American's Alzheimer's Risk Through Exercise-Mild Cognitive Impairment (RAATE-MCI)

Robert L. Newton, Jr. 2021. "Reducing African American's Alzheimer's Risk Through Exercise-Mild Cognitive Impairment (RAATE-MCI)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04956549.

All > Mild Cognitive Impairment