Citicoline Supplement for Alzheimer's Disease
Trial Summary
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What data supports the effectiveness of the drug Citicoline supplement for Alzheimer's disease?
Is citicoline safe for humans?
Citicoline has been used extensively for various neurodegenerative disorders, including Alzheimer's disease, and is generally considered safe in humans. In a study with Alzheimer's patients, no significant safety concerns were reported during a 12-week treatment with citicoline compared to a placebo.16789
How does the drug citicoline differ from other Alzheimer's treatments?
Citicoline is unique because it is an endogenous compound that helps in the production of brain phospholipids and acetylcholine, which are important for brain function. Unlike other Alzheimer's treatments that focus on inhibiting the breakdown of acetylcholine, citicoline supports the synthesis of these essential components, potentially improving cognitive performance.1381011
What is the purpose of this trial?
This trial is testing whether a citicoline supplement can help people with Alzheimer's Disease sleep better and think more clearly. Citicoline may boost brain chemicals that are important for memory and sleep. Citicoline has been extensively used for the treatment of neurodegenerative disorders associated with head trauma, stroke, brain aging, cerebrovascular pathology, and Alzheimer's disease.
Research Team
Victoria Pak, PhD, MS, MTR
Principal Investigator
Emory School of Nursing, School of Public Health
Eligibility Criteria
This trial is for adults with Alzheimer's Disease living in the continental U.S. who can read English and have internet access. It excludes those with severe health issues like heart failure, diabetes type I, liver cirrhosis; psychiatric disorders; sleep apnea; or a history of substance abuse.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either citicoline or placebo for 3 months
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Citicoline supplement
- Placebo
Find a Clinic Near You
Who Is Running the Clinical Trial?
Emory University
Lead Sponsor
National Institute on Aging (NIA)
Collaborator
Goizueta Alzheimer's Disease Research Center (ADRC)
Collaborator