App-Based Contingency Management for Disease

Recruiting · 18+ · All Sexes · Oconomowoc, WI

This study is evaluating whether a set of incentives can help people with opioid use disorders stay clean.

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About the trial for Disease

Eligible Conditions
Opioid Use Disorder (OUD) · Methamphetamine Dependence · Methamphetamine Abuse · Substance-Related Disorders · Disease · Opioid-Related Disorders · Cocaine Use · Substance Use · Opioids Use · Cocaine Use Disorders

Treatment Groups

This trial involves 7 different treatments. App-Based Contingency Management is the primary treatment being studied. Participants will be divided into 6 treatment groups. There is no placebo group. The treatments being tested are in Phase 3 and have had some early promising results.

Experimental Group 1
App-Based Contingency Management
Experimental Group 2
App-Based Contingency Management
Experimental Group 3
App-Based Contingency Management
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This trial is for patients born any sex aged 18 and older. There are 8 eligibility criteria to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
You are eligible for the study if you are at least 18 years old. show original
Meet DSM-5 OUD, CoUD, or MUD criteria as evidenced by an OUD CPT code F11* (opioid related disorders), a CoUD CPT code F14* (cocaine related disorders), a MUD CPT code F15.1/F15.2 or other clinical notes indicating illicit opioid/cocaine/methamphetamine use for treatment;
Have access to a smartphone (iOS or Android) with data plan and willing to download DynamiCare app;
Have an email and can access it from their smartphone;
Are in residential, day (PHP), partial day (IOP), or outpatient (OP) AODA treatment;
Were first enrolled in residential, PHP, or IOP substance use treatment no longer than 2 treatment weeks (14 days/encounters of treatment) prior to providing informed consent.
You have used cocaine, methamphetamine, or opioids within the last 21 days. show original
Understands English.
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Odds of Eligibility
Be sure to apply to 2-3 other trials, as you have a low likelihood of qualifying for this one.Apply To This Trial
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Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: 12 weeks
Screening: ~3 weeks
Treatment: Varies
Reporting: 12 weeks
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: 12 weeks.
View detailed reporting requirements
Trial Expert
Connect with the researchersHop on a 15 minute call & ask questions about:
- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether App-Based Contingency Management will improve 1 primary outcome and 3 secondary outcomes in patients with Disease. Measurement will happen over the course of Time = Day 0 through 12 weeks.

Negative Saliva Analysis Frequency
Percent of random saliva tests classified as negative
Negative Urinalysis Frequency
Percent of standard of care urinalyses results classified as negative
Abstinence from Opioid and/or Cocaine Use
Percent of outcomes saliva tests negative for the relevant drug (opioids and/or cocaine)
Psychotherapy Completion
Whether or not the patient completed the scheduled psychotherapy program.

Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are common treatments for disease?

Results from a recent paper support that medications and surgery are important for treating almost all diseases. Although some drugs are very effective in treating several conditions or diseases, few studies have determined overall treatment success. Furthermore, our findings emphasize the importance of defining what medication(s) is necessary to treat a patient for a given condition or disease and to search for the best ways to use those drugs for the patient and the health system.

Anonymous Patient Answer

What are the signs of disease?

The signs of disease include physical symptoms such an unexplained weight loss and dizziness. Mental symptoms such as social withdrawal, paranoia, and lack of interest in day-to-day activities and problems concentrating on work or at school are also signs of disease.\n

Anonymous Patient Answer

What causes disease?

Some diseases are due to genetic malfunction, whereas other diseases may not be inherited at all. Some diseases are caused by environmental exposure, whereas other diseases may be caused by one's own immune system. For example, some cancers are due to environmental exposure or immune malfunction; others arise as a consequence of an inherited genetic malfunction. Some diseases can be inherited from parents, while others can be acquired from other sources such as the media. Some diseases may also be due to the effects of infection of certain pathogens. All diseases can be caused by multiple factors or by a combination; some pathogens could be the direct cause of disease. Finally, some diseases may be due to a physical change of the body, while others could be the consequence of another disease.

Anonymous Patient Answer

Can disease be cured?

There is a high degree of cure to a large number of patients with early-stage disease. The low cure rates can be a reasonable explanation for low uptake of curative treatment for some patients.

Anonymous Patient Answer

How many people get disease a year in the United States?

The projected lifetime risk of getting HCP is higher-than-expected among US adults. Higher-than-expected numbers were for all cause as well for HCP-related cause. In a recent study, findings of the study have important public health implications that should be addressed in the future development of public health policies to reduce HCP risk and mortality.

Anonymous Patient Answer

What is disease?

The disease term used in this paper was a concise disease definition that clearly delineates the concept of chronic disease in terms of its cause and course; a state of being or being in the process of being disease; and it is a disease with specific treatments. What the term disease implies is discussed.

Anonymous Patient Answer

What is the average age someone gets disease?

The median age at diagnosis is 72 years (range 61 to 86) for all cancer sites for adults with disease, but for leukemia the median age at diagnosis is 58 years (range 46.5 - 69.5). The percentage of newly diagnosed cases of all cancer sites in the general population increased over the past few decades (i.e., 2% to 4% per year) for all adult diagnoses, but only a small percentage of the increase was attributable to a true increase in disease incidence (i.e., 2% to 5% per year). The overall percentage of newly diagnosed cancer cases is likely to increase, because all cancer sites are being diagnosed earlier.

Anonymous Patient Answer

Who should consider clinical trials for disease?

In a recent study, findings shows many possible diseases that might benefit from clinical trials. For some diseases, patients are more likely to participate compared with others. Patients seem to be the best candidate for clinical trials and clinicians, but we should reassure all patients that these trials may be the best treatment choices for only some of the diseases.

Anonymous Patient Answer

Does app-based contingency management improve quality of life for those with disease?

Both treatment groups improved their QOL, but there was significantly greater improvement in both PGC-I and PGC-II for those in the ALC treatment group. PGC-I scores were also significantly higher in the ALC than in the GIS-I and CG-I treatment groups. These positive improvements can be attributed, in part, to the increased self-efficacy of PGC-I participants in the ALC treatment group as well as the motivational benefits of ALC. This benefit is especially noted among PGC-II participants who have demonstrated a desire to improve their quality of life through participation in the study.

Anonymous Patient Answer

How does app-based contingency management work?

In a recent study, findings showed promise in engaging chronically ill alcohol-dependent smokers in mobile applications, and suggested that mobile-based addiction treatment could effectively be developed into an app experience. Additionally, these findings would inform the development of future randomized trials aimed at assessing the efficacy of mCM in this population.

Anonymous Patient Answer

How serious can disease be?

Patients with the [full-range of MDA parameters]] tended to be at significant risk for cardiovascular disease at the time of diagnosis (in general, all patients with MDA parameters above the median were at a >10% increased risk). Despite this, patients' subjective quality of life and outlook were generally poor, and patients often required clinical interventions. MDA parameters may constitute important markers of disease severity for patients with MDA.

Anonymous Patient Answer

What is app-based contingency management?

Using Power will not only help you find appropriate clinical trials for your current diagnosis, it helps you find other clinical research studies that could help you manage tinnitus. To manage app-based contingency management, patients need to manage both their tinnitus and their digital trackers.

Anonymous Patient Answer
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