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Behavioural Intervention

Digital Intervention for Depression

Waitlist Available
Research Sponsored by University of Texas at Austin
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Screening 3 weeks
Treatment Varies
Follow Up daily over 4 weeks
Awards & highlights

Study Summary

This trial tests a digital intervention to reduce depression and rumination in individuals with elevated symptoms. Participants use the intervention for 4 weeks & complete daily & weekly surveys.

Who is the study for?
This trial is for individuals with moderate or severe depression symptoms who focus more on sad faces, can give informed consent, speak English fluently, and have stable medication use. They need a smartphone and computer access but cannot join if they heavily use alcohol or have serious mental illnesses like schizophrenia.Check my eligibility
What is being tested?
The study tests a gamified app designed to shift attention away from negative stimuli as a treatment for depression. Participants will engage with the app daily over four weeks and complete short surveys plus weekly assessments.See study design
What are the potential side effects?
Since this is a digital intervention focusing on attention training through an app, there are no direct physical side effects expected. However, users may experience frustration or lack of interest in the game-like tasks.


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~daily over 4 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and daily over 4 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Patient Health Questionnaire - 8 (PHQ-8)
Secondary outcome measures
Perseverative Thinking Questionnaire (PTQ) -"Difficult to Disengage from" subscale
Ruminative Response Scale - Brooding subscale (RRS-B)
Other outcome measures
Attention bias (mousetracking)
General Rumination

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: Gamified Attention Bias ModificationActive Control1 Intervention
Digital therapeutic intervention based on Attention Bias Modification Training (ABMT) designed to decrease negative attention bias.
Group II: Gamified Placebo TrainingPlacebo Group1 Intervention
Identical version of the gamified behavioral intervention without manipulation designed to decrease negative attention bias

Find a Location

Who is running the clinical trial?

University of Texas at AustinLead Sponsor
358 Previous Clinical Trials
81,603 Total Patients Enrolled
31 Trials studying Depression
5,179 Patients Enrolled for Depression

Media Library

Gamified Attention Bias Modification (Behavioural Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05601362 — N/A
Depression Research Study Groups: Gamified Attention Bias Modification, Gamified Placebo Training
Depression Clinical Trial 2023: Gamified Attention Bias Modification Highlights & Side Effects. Trial Name: NCT05601362 — N/A
Gamified Attention Bias Modification (Behavioural Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05601362 — N/A
~51 spots leftby Jun 2025