← Back to Search

Behavioural Intervention

Expiratory Muscle Strength Training (EMST-150) for Amyotrophic Lateral Sclerosis

N/A
Waitlist Available
Led By Jessica E Huber, Ph.D.
Research Sponsored by Purdue University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up measured each week of training across the entire training duration
Awards & highlights

Study Summary

This trial is testing a new way to treat early stage ALS that could improve communication, cough response, and respiratory strength.

Eligible Conditions
  • Amyotrophic Lateral Sclerosis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline 2 (week 2), pre-training (week 3), post-training (week 10)
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline 2 (week 2), pre-training (week 3), post-training (week 10) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change From Baseline to Post-treatment for Maximum Expiratory Pressure
Secondary outcome measures
ALS Function Rating Scale Revised
Adherence to Training Protocol
Change From Baseline to Post-Treatment in ALS Quality of Life Scale
+8 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Expiratory Muscle Strength TrainingExperimental Treatment1 Intervention
All participants will forcefully breathe out into an Expiratory Muscle Strength Training device (EMST-150) 25 times per day for 6 weeks. The EMST device will be set at a moderate intensity level (50% of each participant's maximum expiratory pressure).
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Expiratory Muscle Strength Training (EMST-150)
2021
N/A
~20

Find a Location

Who is running the clinical trial?

Purdue UniversityLead Sponsor
224 Previous Clinical Trials
72,751 Total Patients Enrolled
National Institute on Deafness and Other Communication Disorders (NIDCD)NIH
328 Previous Clinical Trials
178,283 Total Patients Enrolled
5 Trials studying Amyotrophic Lateral Sclerosis
159 Patients Enrolled for Amyotrophic Lateral Sclerosis
Jessica E Huber, Ph.D.Principal InvestigatorPurdue University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who else is applying?

How old are they?
65+
What portion of applicants met pre-screening criteria?
Met criteria
Recent research and studies
clinicaltrials.govStudy
Effectiveness of Expiratory Muscle Strength Training for Improving Communication in ALS
HuberLab 2021. "Effectiveness of Expiratory Muscle Strength Training for Improving Communication in ALS". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05003167.
~3 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top