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TAP block for Breast Cancer

N/A
Waitlist Available
Led By Moein Momtazi, MD
Research Sponsored by Ottawa Hospital Research Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1st, 2nd, 4th, 8th, 12th, 16th and 24th postoperative hours
Awards & highlights

Study Summary

This trial will compare two types of blocks used to numb the area after DIEP flap breast reconstruction to see which results in a better recovery.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1st, 2nd, 4th, 8th, 12th, 16th and 24th postoperative hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1st, 2nd, 4th, 8th, 12th, 16th and 24th postoperative hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Secondary outcome measures
Ambulation
Block complication
Pain visual analog scale
+5 more

Trial Design

2Treatment groups
Active Control
Group I: TAP blockActive Control1 Intervention
All patients will have paravertebral (PV) blocks of the chest performed prior to induction of general anesthesia. Patients in this group will have bilateral sham blocks performed after PV block is complete. 2ml of normal saline will be injected under the skin bilaterally near the insertion site of a typical QL block. TAP block will be performed intraoperatively by the surgeon. The anesthesiologist will provide the surgeon with 40ml of LA mixture (ropivacaine 0.25%, epinephrine 100mcg and dexamethasone 4mg) for patients in this group. The surgeon will be blinded to the injectate content. The TAP block is performed once the abdominal flap has been harvested. The triangle of Petit is landmarked by the iliac crest inferiorly, the latissimus dorsi muscle posteriorly and the external oblique muscle anteriorly. A blunt tip needle is advanced through the external oblique fascia and internal oblique fascia. A total volume 20mL of the LA mixture will be injected per side.
Group II: QL blockActive Control1 Intervention
All patients will have paravertebral (PV) blocks of the chest performed prior to induction of general anesthesia. Patients in this group will have QL block performed after PV block is complete. This will be performed with patients in the prone position using the transverse in-plane technique. With realtime U/S guidance, the quadratus lumborum muscle is identified before a short-bevel needle is advanced into the plane between the quadratus lumborum and psoas major muscles. Needle tip position is confirmed by separation of quadratus lumborum and psoas major upon injection. 20ml of ropivacaine 0.25%, epinephrine 50mcg and dexamethasone 2mg will be injected per side. TAP block is performed intraoperatively similar to above but with 40mL of normal saline to perform a sham block. The anesthesiologist will provide the surgeon with 40ml of normal saline in this group. The surgeon will be blinded to the injectate content.

Find a Location

Who is running the clinical trial?

Ottawa Hospital Research InstituteLead Sponsor
561 Previous Clinical Trials
2,785,691 Total Patients Enrolled
34 Trials studying Breast Cancer
5,261 Patients Enrolled for Breast Cancer
Moein Momtazi, MDPrincipal InvestigatorOttawa Hospital Research Institute
1 Previous Clinical Trials

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any openings for participation in this trial at present?

"According to clinicaltrials.gov, this medical trial has not been recruiting since it was updated on March 19th 2022. Despite the lack of recruitment for this specific study, there are more than 1400 other studies actively seeking participants."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
TAP vs QL for Postoperative Analgesia After DIEP Free Flap Breast Reconstruction
Moein Momtazi 2022. "TAP vs QL for Postoperative Analgesia After DIEP Free Flap Breast Reconstruction". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05301595.
~0 spots leftby Apr 2025
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