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Niacin and Aspirin for Prostaglandin D2 Metabolism Pathways
Study Summary
This trialis studying a previously unknown pathway between two compounds that help with inflammation. It is testing if one of these compounds is made from the other.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I have used over-the-counter pain or anti-inflammatory medications within the last 2 weeks.I am healthy and not on any medications.
- Group 1: deuterated PGD2
- Group 2: niacin + regular-strength aspirin
- Group 3: niacin
- Group 4: niacin + low-dose aspirin
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Does this research allow for participants that are not yet 20 years of age?
"Eligibility for this study is restricted to patients aged 18-65. However, there are 17 other clinical trials open to participants that are under 18 and 168 trials for seniors."
What are the benefits of PGD2?
"PGD2 is most commonly used as treatment for percutaneous coronary intervention (pci). However, it has also been taken to treat multiple other conditions such as dental procedures, inflammation, and neck pain."
Have patients undergone this exact treatment before in other clinical trials?
"To date, there have been 180 ongoing clinical trials for PGD2 in 61 different countries and 1450 cities. The first such trial was sponsored by Sanofi and completed Phase 3 drug approval in 2002 with 413 participants. In the 18 years since then, 510 more trials have completed."
Are volunteers still needed for this research study?
"According to the latest information available on clinicaltrials.gov, this trial is not presently recruiting new participants. The study was first made public on January 14th, 2021 and received its last update on October 8th, 2022. Even though this particular trial has completed recruitment, there are still 181 other trials that are looking for candidates."
Who would this trial be most beneficial for?
"This trial is only considering patients that have bleomycin b2 and are between 18-65 years old, with a total of 10 people being accepted into the study."
How many people are being monitored as part of this research project?
"Unfortunately, this particular study is no longer seeking candidates. The trial was first posted on January 14th, 2021 and was updated for the last time on October 28th, 2022. However, there are 1 clinical trials actively enrolling patients with bleomycin b2 and 180 other studies involving PGD2 that are currently looking for participants."
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