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Antiplatelet agent
Ticagrelor Arm for Acute Coronary Syndrome (CPRS-CKD Trial)
Phase 4
Waitlist Available
Research Sponsored by North Texas Veterans Healthcare System
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 year from date of admission
Awards & highlights
CPRS-CKD Trial Summary
To compare clinical outcomes in patients with chronic kidney disease (CKD) presenting with an acute coronary syndrome (ACS) treated with clopidogrel or ticagrelor (both FDA approved and guideline indicated drugs for treating these patients upstream managed medically or with coronary revascularization).
Eligible Conditions
- Acute Coronary Syndrome
- Chronic Kidney Disease
CPRS-CKD Trial Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 1 year from date of admission
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 year from date of admission
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Occurrence of all-cause mortality, non-fatal myocardial infarction (MI), or ischemic stroke
Secondary outcome measures
Length of hospital stay and readmission
Need for ischemia driven urgent coronary revascularization
Occurrence of MACE events
+1 moreCPRS-CKD Trial Design
2Treatment groups
Active Control
Group I: Ticagrelor ArmActive Control1 Intervention
Eligible patients randomized to the Ticagrelor arm will receive open label drug at a dose selected by their providers along with 81mg aspirin. These patients will be followed for 1 year through chart review for events. For event free patients, a phone follow-up will be done at the end of 1 year to record events These events be documented in the medical records.
Group II: ClopidogrelActive Control1 Intervention
Eligible patients randomized to the Clopidogrel arm will receive open label drug at a dose selected by their providers along with 81mg aspirin. These patients will be followed for 1 year through chart review for events. For event free patients, a phone follow-up will be done at the end of 1 year to record events These events be documented in the medical records
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Who is running the clinical trial?
North Texas Veterans Healthcare SystemLead Sponsor
37 Previous Clinical Trials
4,004,425 Total Patients Enrolled
1 Trials studying Acute Coronary Syndrome
40 Patients Enrolled for Acute Coronary Syndrome
Frequently Asked Questions
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