← Back to Search

PSMA PET Scans for Prostate Cancer

Q: Are participants being accepted for this clinical research currently?

<p>The trial posted on clinicaltrials.gov is not currently seeking participants; the last update occurred on September 16th, 2022. However, there are presently 2304 other comparable studies that do accept new volunteers for participation.</p>

Phase < 1

Waitlist Available

Led By Val Lowe, M.D.

Research Sponsored by Mayo Clinic

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Histopathological proven prostate adenocarcinoma.

Rising PSA after definitive therapy with prostatectomy or radiation therapy (external beam or brachytherapy).

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 12 months

Awards & highlights

Study Summary

This trial is testing how well two different imaging methods work in detecting prostate cancer.

Who is the study for?

Men over 18 with recurrent prostate cancer after surgery or radiation, who can sign consent and have a certain level of physical ability (Karnofsky score of 50). They must not be on other prostate cancer treatments except for some hormone therapies if resistant. No recent other cancers or ongoing investigational therapies.Check my eligibility

What is being tested?

The trial is testing two imaging agents, F-18 PSMA 1007 and Ga-68 PSMA11, to see how well they detect metastatic prostate cancer in patients with rising PSA levels post-treatment.See study design

What are the potential side effects?

Potential side effects are related to the PET scan procedure and may include reactions to the imaging agents like mild irritation or discomfort at the injection site. Allergic reactions are possible but rare.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

My prostate cancer is confirmed by tissue analysis.

Select...

My PSA levels are increasing after prostate cancer surgery or radiation.

Select...

I need considerable assistance and medical care.

Select...

I am older than 18 years.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 12 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~12 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Tumor Detection on PET/CT

Secondary outcome measures

Impact of PSMA and C-11 choline PET on clinical management

Incidence of adverse events attributable to PSMA

Trial Design

2Treatment groups

Experimental Treatment

Group I: PET/CT Ga-68 PSMAExperimental Treatment1 Intervention

Ga-68 labeled PSMA-11 (or PSMA-HBED-CC) PET/CT

Group II: PET/CT F-18 Labeled PSMA 1007Experimental Treatment1 Intervention

F-18 Labeled PSMA 1007 PET/CT

0 / 4Eligibility criteria met

Find a Location

Who is running the clinical trial?

Mayo ClinicLead Sponsor

3,207 Previous Clinical Trials

3,766,890 Total Patients Enrolled

33 Trials studying Prostate Cancer

8,138 Patients Enrolled for Prostate Cancer

Val Lowe, M.D.Principal InvestigatorMayo Clinic

1 Previous Clinical Trials

8,000 Total Patients Enrolled

Media Library

Ga-68 PSMA11 Clinical Trial Eligibility Overview. Trial Name: NCT03768349 — Phase < 1

Prostate Cancer Research Study Groups: PET/CT Ga-68 PSMA, PET/CT F-18 Labeled PSMA 1007

Prostate Cancer Clinical Trial 2023: Ga-68 PSMA11 Highlights & Side Effects. Trial Name: NCT03768349 — Phase < 1

Ga-68 PSMA11 2023 Treatment Timeline for Medical Study. Trial Name: NCT03768349 — Phase < 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are participants being accepted for this clinical research currently?

"The trial posted on clinicaltrials.gov is not currently seeking participants; the last update occurred on September 16th, 2022. However, there are presently 2304 other comparable studies that do accept new volunteers for participation."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

PSMA and C-11 Choline PET in Patients With Biochemical Recurrence of Prostate Cancer

Val Lowe 2019. "PSMA and C-11 Choline PET in Patients With Biochemical Recurrence of Prostate Cancer". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03768349.