Vandetanib for Lung Cancer (ZEAL Trial)

"Unfortunately, this particular trial is no longer looking for patients. Although, it's worth mentioning that there are presently 2237 other studies searching for patients with lung cancer and 244 trials involving Pemetrexed that are actively enrolling participants."

"Pemetrexed is most frequently used to medicate adrenal medulla, however it can also be given as treatment for other issues such as ovarian cancer, unresectable thymoma, and locally advanced nonsquamous non-small cell lung cancer."

"The key metric that will be used to judge the success of this clinical trial is Progression-Free Survival (PFS) in the Female Population, which will be assessed every 6 weeks over the course of the study. Additionally, Secondary outcomes including Longitudinal Analysis of Average Symptom Burden Index (ASBI) Score and Objective Response Rate (ORR) will also be monitored."

"Pemetrexed receives a 3 because it is in Phase 3 clinical trials. This indicates that while there is some data supporting efficacy, multiple rounds of testing have supported its safety profile."

"Currently, this trial is taking place in 23 different locations. They are situated in Middletown, Hilton Head Island and Washington among other places. If you enroll in the study, try to choose a site near you to avoid excessive travel."

"The clinical trial in question, which was first posted on 1/1/2007 and last updated on 10/3/2022, is not looking for any more participants at this time. However, there are 2481 other trials that are still recruiting patients."

"Pemetrexed was first studied in 2005 by Hematology-Oncology Associates of Illinois. Since then, there have been 353 completed clinical trials. As of now, 244 studies are still active; a large number of these are based out of Middletown, Ohio."