N-acetylcysteine for Alcoholism

Phase-Based Progress Estimates
1
Effectiveness
2
Safety
AlcoholismN-acetylcysteine - Drug
Eligibility
13 - 25
All Sexes
What conditions do you have?
Select

Study Summary

This trial is testing if N-acetylcysteine can help reduce alcohol use in adolescents with alcohol use disorder.

Eligible Conditions
  • Alcoholism

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 0 Secondary · Reporting Duration: 8 weeks of treatment

8 weeks of treatment
Reduction in alcohol use

Trial Safety

Safety Progress

2 of 3
This is further along than 68% of similar trials

Trial Design

2 Treatment Groups

N-acetylcysteine
1 of 2
Placebo
1 of 2

Experimental Treatment

Non-Treatment Group

120 Total Participants · 2 Treatment Groups

Primary Treatment: N-acetylcysteine · Has Placebo Group · Phase 2

N-acetylcysteine
Drug
Experimental Group · 1 Intervention: N-acetylcysteine · Intervention Types: Drug
Placebo
Drug
PlaceboComparator Group · 1 Intervention: Placebo oral capsule · Intervention Types: Drug
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Acetylcysteine
FDA approved

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 8 weeks of treatment

Who is running the clinical trial?

Medical University of South CarolinaLead Sponsor
838 Previous Clinical Trials
5,378,464 Total Patients Enrolled
42 Trials studying Alcoholism
4,581 Patients Enrolled for Alcoholism
Kevin M Gray, MDPrincipal InvestigatorProfessor of Psychiatry and Behavioral Sciences
7 Previous Clinical Trials
958 Total Patients Enrolled

Eligibility Criteria

Age 13 - 25 · All Participants · 5 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
are considerably more likely to develop DSM-5 alcohol use disorder during their young adulthood
The study participant must be able to understand the study and provide written informed consent
The person has met certain criteria for an alcohol use disorder.
Females who participate in the study must agree to use appropriate birth control methods, which include oral contraceptives, a contraceptive patch, barrier contraception (diaphragm or condom), a levonorgestrel implant, medroxyprogesterone acetate, complete abstinence from sexual intercourse, or a hormonal contraceptive vaginal ring.