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Study Summary
This trial will compare the effects of avelumab plus best supportive care versus best supportive care alone on survival in patients with locally advanced or metastatic urothelial cancer.
Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2020 Phase 2 trial • 19 Patients • NCT03006848Trial Design
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Who is running the clinical trial?
Frequently Asked Questions
Have similar tests been run before?
"Currently, there are 116 global clinical trials underway for Avelumab in over 1000 cities across 52 countries. The first trial began in 2014 and was sponsored by EMD Serono Research & Development Institute, Inc. That initial study involved 204 patients and completed Phase 2 drug approval. To date, 70 total trials have been completed since 2014."
What is the general efficacy of Avelumab in past studies?
"Port Macquarie Base Hospital was the first medical institution to study avelumab in 2014. Since then, there have been 70 completed studies with 116 more presently ongoing. Many of these active trials are being conducted out of Aurora, Colorado."
How many individuals are being welcomed into this research project?
"Unfortunately, this trial is not currently open for recruitment. The listing was created on April 25th, 2016 and last updated on October 24th, 2022. However, there are other trials that may be of interest. There are 32 urothelial cancer studies and 116 Avelumab trials that are still seeking participants."
What are some of the dangers patients face when taking Avelumab?
"Avelumab is classified as a 3 on our Power team's safety scale. This is due to the fact that it has reached Phase 3 in clinical trials, meaning that there is both anecdotal and empirical evidence supporting its efficacy and safety."
Are there many different places in America where this clinical trial is taking place?
"There are a total of 19 locations running this clinical trial, some of which include University of Colorado Denver, CTO (CTRC) in Aurora, University of Colorado Hospital - Anschutz Inpatient Pavilion (AIP) in New Haven, and Smilow Cancer Hospital at Yale-New Haven in Seattle."
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