Your session is about to expire
← Back to Search
Anti-metabolites
Combination Cream for Squamous Cell Carcinoma
Phase < 1
Recruiting
Led By Joshua D Eikenberg, MD
Research Sponsored by Carilion Clinic
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6-8 wks
Awards & highlights
Study Summary
This trialwill test if combining two creams can treat skin cancer with fewer side effects and a shorter treatment duration.
Eligible Conditions
- Squamous Cell Carcinoma
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 6-8 wks
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6-8 wks
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Cancer resolution on histopathology
Secondary outcome measures
Cosmetic appearance
Final scar length
Trial Design
3Treatment groups
Experimental Treatment
Placebo Group
Group I: 7 day medication groupExperimental Treatment1 Intervention
The 7 day medication group will apply combination topical 5-fluorouracil 5% / calcipotriene 0.005% cream twice per day for 7 days.
Group II: 14 day medication groupExperimental Treatment1 Intervention
The 14 day medication group will apply combination topical 5-fluorouracil 5% / calcipotriene 0.005% cream twice per day for 14 days.
Group III: Placebo groupPlacebo Group1 Intervention
10 patients will be divided into 7 and 14 day treatment groups with 5 patients each. They will apply Nourivan base cream from Pure Science Rx, twice per day for their designated time.
Find a Location
Who is running the clinical trial?
Carilion ClinicLead Sponsor
70 Previous Clinical Trials
12,685 Total Patients Enrolled
Joshua D Eikenberg, MDPrincipal InvestigatorCarilion Clinic Dermatology
Mariana Phillips, MDPrincipal InvestigatorCarilion Clinic Dermatology
1 Previous Clinical Trials
1,600 Total Patients Enrolled
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- You cannot have surgery to remove something from your body due to a medical reason.Your tumor has come back after previous treatment.Your immune system is weak or suppressed.The tumors should not have any hard or lumpy areas.
Research Study Groups:
This trial has the following groups:- Group 1: 14 day medication group
- Group 2: 7 day medication group
- Group 3: Placebo group
Awards:
This trial has 2 awards, including:- Approved for 5 Other Conditions - This treatment demonstrated efficacy for 5 other conditions.
- All Individual Drugs Already Approved - Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Other Trials to Consider
Popular Categories
Share this study with friends
Copy Link
Messenger