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Solaraze + Vaniqa for Skin Cancer
Study Summary
This trial is testing whether a topical combination of drugs can prevent skin cancer in people who have had skin cancer in the past.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I am older than 18 years.I agree to use birth control during the study.I have not had cryotherapy on my forearms in the last 3 months.I am using topical steroids on my forearms.I haven't had skin treatments like peels or laser on my forearms in the last 6 months.I am using birth control and have a negative pregnancy test.I am not using certain skin or cancer treatments, and I am not pregnant or breastfeeding.I do not have any serious illnesses that are not under control.I haven't had major surgery or cancer treatment in the last 4 weeks.I take more than 100 mg of aspirin daily.I regularly take NSAIDs or COX-2 inhibitors.I have been on steroids for more than 2 weeks.I have a history of serious health conditions or reactions to certain medications.I am willing to stop using certain skin creams, pain relievers, and my blood tests meet specific requirements.I am fully active or can carry out light work.I had early-stage skin cancer treatment and now have actinic keratosis.A close family member has Ornithine Transcarbamylase Deficiency.
- Group 1: Placebo + Placebo
- Group 2: Diclofenac + DFMO
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is the combination of Diclofenac and DFMO tolerable for humans?
"The safety of the combination drug Diclofenac + DFMO has been assessed as a 2. This is because, while Phase 2 trials have documented data on its security, there are no studies yet that look into its efficacy."
Is this research program currently recruiting participants?
"According to clinicaltrials.gov, this study is actively searching for participants and has been since January 18th 2021. Recently, the trial details have been updated as of November 14th 2022."
What therapeutic purpose is Diclofenac + DFMO typically prescribed for?
"Diclofenac + DFMO is frequently prescribed to treat catarrh, but it can also be beneficial for photorefractive keratectomy, muscle strain and hand osteoarthritis."
How many individuals are engaged in this clinical assessment?
"Affirmative. Data hosted on clinicaltrials.gov confirms that this medical study, which was first posted on January 18th 2021, is actively enrolling participants. 138 individuals are needed from three distinct medical facilities."
Have researchers conducted any other investigations on the combination of Diclofenac and DFMO?
"Currently, 28 trials are researching the efficacy of Diclofenac + DFMO. Out of these studies, 7 have entered Phase 3 of clinical testing. Although Mooresville, North carolina is home to many experiments on this combination therapy, it can be administered in 1,423 sites across the US."
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