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Veterans Affairs Medical Center - Cincinnati

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Cincinnati, Ohio 45220
Global Leader in Lung Cancer
Global Leader in Post-Traumatic Stress Disorder
Conducts research for Lymphoma
Conducts research for Leukemia
Conducts research for Non-Small Cell Lung Cancer
150 reported clinical trials
6 medical researchers
Photo of Veterans Affairs Medical Center - Cincinnati in CincinnatiPhoto of Veterans Affairs Medical Center - Cincinnati in CincinnatiPhoto of Veterans Affairs Medical Center - Cincinnati in Cincinnati

Summary

Veterans Affairs Medical Center - Cincinnati is a medical facility located in Cincinnati, Ohio. This center is recognized for care of Lung Cancer, Post-Traumatic Stress Disorder, Lymphoma, Leukemia, Non-Small Cell Lung Cancer and other specialties. Veterans Affairs Medical Center - Cincinnati is involved with conducting 150 clinical trials across 170 conditions. There are 6 research doctors associated with this hospital, such as Charuhas Thakar, MD, Robert Burkes, MD, Hanan Kerr, MD, and Jack Rubinstein, MD.

Top PIs

Clinical Trials running at Veterans Affairs Medical Center - Cincinnati

Post-Traumatic Stress Disorder
Atherosclerosis
Heart Failure
Contrast-induced Nephropathy
Diabetic Kidney Disease
Insomnia
Incretin Hormones in Polycystic Ovary Syndrome
Prediabetes
Metformin
Cardiovascular Disease
Image of trial facility.

Adapted Cognitive Processing Therapy

for PTSD

Cognitive Processing Therapy (CPT) consists of discrete therapeutic components that are delivered across 12 sessions, but most Veterans never reach session 12, and those who drop out receive only 4 sessions on average. Veterans drop out because of time constraints, logistics, and lack of perceived benefit. Unfortunately, Veterans who drop out prematurely may never receive the most effective components of CPT and continue to experience symptom-related distress and numerous other negative outcomes, including lost productivity, substance use, later-life physical disability, reduced quality of life, and increased risk of suicide. The overall objective of this study is to adapt CPT into a brief, effective format. The rationale is that identifying the most effective intervention components and delivering only those components will make CPT deliverable in a shorter timeframe, thus improving efficiency, reducing drop-out related to poor treatment response, and ensuring that Veterans receive the most beneficial components of treatment, which will significantly improve their quality of life.
Recruiting1 award N/A
Image of trial facility.

Family Involvement

for PTSD

Although effective treatments for PTSD exist, high rates of treatment dropout and sub-optimal response rates remain common. Incorporating family members in treatment represents one avenue for improving outcomes and providing Veteran-centered care, and surveys of Veterans in outpatient VA PTSD care indicate that 80% desire family involvement. The VA has invested many years and millions of dollars on the dissemination of Cognitive Processing Therapy (CPT) and Prolonged Exposure (PE) for PTSD. A family-based intervention that complements these two first-line treatments would capitalize on existing treatment infrastructure while also potentially boosting outcomes and retention. Preliminary testing of the proposed Brief Family Intervention (BFI) resulted in 50% less dropout from CPT/PE among Veterans whose family members received the BFI. There was also a large impact on PTSD symptoms at 16 weeks (d = 1.12) in favor of the BFI group. The goal of this study is to test the effectiveness of the BFI among a fully-powered sample. One hundred Veteran-family member dyads (n = 200) will be recruited. Veterans will be beginning a course of usual-care CPT or PE at one of two VA sites. Family members will be randomized to receive or not receive the BFI, a two-session psychoeducational and skills-based protocol. PTSD symptom severity and treatment retention will be the primary outcomes. Assessments will be conducted by independent evaluators at baseline, 6-, 12-, 18-, and 26-weeks. Veterans whose family members receive the BFI are expected to have lower dropout and a greater rate of change in their PTSD symptoms compared to Veterans whose family members do not receive the BFI. If the BFI is found to increase the effectiveness of and retention in CPT/PE, it will be a highly appealing option for incorporating families into Veterans' PTSD care.
Recruiting1 award N/A9 criteria

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Frequently asked questions

What kind of research happens at Veterans Affairs Medical Center - Cincinnati?
Veterans Affairs Medical Center - Cincinnati is a medical facility located in Cincinnati, Ohio. This center is recognized for care of Lung Cancer, Post-Traumatic Stress Disorder, Lymphoma, Leukemia, Non-Small Cell Lung Cancer and other specialties. Veterans Affairs Medical Center - Cincinnati is involved with conducting 150 clinical trials across 170 conditions. There are 6 research doctors associated with this hospital, such as Charuhas Thakar, MD, Robert Burkes, MD, Hanan Kerr, MD, and Jack Rubinstein, MD.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
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Terms of Service·Privacy Policy·Cookies·Security
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top
Terms of Service·Privacy Policy·Cookies·Security