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Veterans Affairs Medical Center - Cincinnati
Claim this profileCincinnati, Ohio 45220
Global Leader in Lung Cancer
Global Leader in Post-Traumatic Stress Disorder
Conducts research for Leukemia
Conducts research for Breast Cancer
Conducts research for Lymphoma
150 reported clinical trials
6 medical researchers
Summary
Veterans Affairs Medical Center - Cincinnati is a medical facility located in Cincinnati, Ohio. This center is recognized for care of Lung Cancer, Post-Traumatic Stress Disorder, Leukemia, Breast Cancer, Lymphoma and other specialties. Veterans Affairs Medical Center - Cincinnati is involved with conducting 150 clinical trials across 180 conditions. There are 6 research doctors associated with this hospital, such as Charuhas Thakar, MD, Robert Burkes, MD, Jack Rubinstein, MD, and Hanan Kerr, MD.Top PIs
Charuhas Thakar, MDCincinnati VA Medical Center6 years of reported clinical research
Studies IgA Nephropathy
Studies Immunoglobulin A Nephropathy
2 reported clinical trials
3 drugs studied
Robert Burkes, MDCincinnati VA Hospital3 years of reported clinical research
Studies Chronic Obstructive Pulmonary Disease
2 reported clinical trials
3 drugs studied
Jack Rubinstein, MDCincinnati VA Medical Center, Cincinnati, OH4 years of reported clinical research
Studies Heart Failure
1 reported clinical trial
2 drugs studied
Hanan Kerr, MDCincinnati VA Medical Center, Cincinnati, OH2 years of reported clinical research
Studies Stroke
Studies Peripheral Artery Disease
1 reported clinical trial
2 drugs studied
Clinical Trials running at Veterans Affairs Medical Center - Cincinnati
Post-Traumatic Stress Disorder
Bladder Cancer
Atherosclerosis
Diabetic Kidney Disease
Chronic Obstructive Pulmonary Disease
Peripheral Artery Disease
Coronary Artery Disease
Cerebrovascular Disease
Incretin Hormones in Polycystic Ovary Syndrome
Prediabetes
Therapist Training
for PTSD
Cognitive Processing Therapy (CPT) is highly effective in randomized controlled trials, but its effectiveness drops substantially in standard clinical practice, largely due to therapist "drift" from fidelity to the protocol. What remains unknown is which components of CPT training yield high therapist fidelity. Thus, there is a critical need to use empirical approaches to identify the most effective components of CPT training and to develop an adaptive training model for CPT by testing sequences of empirically-supported training strategies. The long-term goal of this research is to develop a sustainable model of therapy training that is personalized to the needs of the therapist trainee. The overall objective of this application is to empirically optimize an adaptive model for CPT training. The rationale is that developing an adaptive training model will improve efficiency and personalization, yield higher fidelity, and ultimately improve Veteran outcomes. We expect that completion of this project will produce an adaptive CPT training program that yields high therapist fidelity. Improving CPT fidelity in VHA will have a positive impact on the health and wellbeing of Veterans with PTSD.
Recruiting1 award N/A1 criteria
Family Involvement
for PTSD
Although effective treatments for PTSD exist, high rates of treatment dropout and sub-optimal response rates remain common. Incorporating family members in treatment represents one avenue for improving outcomes and providing Veteran-centered care, and surveys of Veterans in outpatient VA PTSD care indicate that 80% desire family involvement. The VA has invested many years and millions of dollars on the dissemination of Cognitive Processing Therapy (CPT) and Prolonged Exposure (PE) for PTSD. A family-based intervention that complements these two first-line treatments would capitalize on existing treatment infrastructure while also potentially boosting outcomes and retention. Preliminary testing of the proposed Brief Family Intervention (BFI) resulted in 50% less dropout from CPT/PE among Veterans whose family members received the BFI. There was also a large impact on PTSD symptoms at 16 weeks (d = 1.12) in favor of the BFI group. The goal of this study is to test the effectiveness of the BFI among a fully-powered sample. One hundred Veteran-family member dyads (n = 200) will be recruited. Veterans will be beginning a course of usual-care CPT or PE at one of two VA sites. Family members will be randomized to receive or not receive the BFI, a two-session psychoeducational and skills-based protocol. PTSD symptom severity and treatment retention will be the primary outcomes. Assessments will be conducted by independent evaluators at baseline, 6-, 12-, 18-, and 26-weeks. Veterans whose family members receive the BFI are expected to have lower dropout and a greater rate of change in their PTSD symptoms compared to Veterans whose family members do not receive the BFI. If the BFI is found to increase the effectiveness of and retention in CPT/PE, it will be a highly appealing option for incorporating families into Veterans' PTSD care.
Recruiting1 award N/A9 criteria
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Frequently asked questions
What kind of research happens at Veterans Affairs Medical Center - Cincinnati?
Veterans Affairs Medical Center - Cincinnati is a medical facility located in Cincinnati, Ohio. This center is recognized for care of Lung Cancer, Post-Traumatic Stress Disorder, Leukemia, Breast Cancer, Lymphoma and other specialties. Veterans Affairs Medical Center - Cincinnati is involved with conducting 150 clinical trials across 180 conditions. There are 6 research doctors associated with this hospital, such as Charuhas Thakar, MD, Robert Burkes, MD, Jack Rubinstein, MD, and Hanan Kerr, MD.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.