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Children's Hospital of Orange County
Claim this profileOrange, California 92868
Global Leader in T-Lymphoblastic Leukemia/Lymphoma
Global Leader in Uterine Tumors
Conducts research for Lymphoma
Conducts research for Brain Tumor
Conducts research for Acute Lymphoblastic Leukemia
527 reported clinical trials
22 medical researchers
Summary
Children's Hospital of Orange County is a medical facility located in Orange, California. This center is recognized for care of T-Lymphoblastic Leukemia/Lymphoma, Uterine Tumors, Lymphoma, Brain Tumor, Acute Lymphoblastic Leukemia and other specialties. Children's Hospital of Orange County is involved with conducting 527 clinical trials across 828 conditions. There are 22 research doctors associated with this hospital, such as Elyssa M. Rubin, Mariko Sato, Josephine H. Haduong, and Raymond Wang, MD.Area of expertise
1T-Lymphoblastic Leukemia/Lymphoma
Global LeaderStage III
Stage IV
Stage II
2Uterine Tumors
Global LeaderStage IV
Stage I
Stage II
Top PIs
Elyssa M. RubinChildren's Hospital of Orange County7 years of reported clinical research
Expert in Uterine Tumors
Expert in Neuroblastoma
53 reported clinical trials
108 drugs studied
Mariko SatoUniversity of Iowa/Holden Comprehensive Cancer Center7 years of reported clinical research
Expert in Cerebral Gliomas
Expert in Uterine Tumors
49 reported clinical trials
95 drugs studied
Josephine H. HaduongChildren's Hospital of Orange County9 years of reported clinical research
Studies Relapse
Studies Uterine Tumors
13 reported clinical trials
22 drugs studied
Raymond Wang, MDChildren's Hospital of Orange County (CHOC)2 years of reported clinical research
Studies Mucopolysaccharidosis
Studies Krabbe Disease
7 reported clinical trials
7 drugs studied
Clinical Trials running at Children's Hospital of Orange County
Brain Tumor
Cancer
Acute Lymphoblastic Leukemia
T-Lymphoblastic Leukemia/Lymphoma
Lymphoma
Uterine Tumors
Testicular cancer
Relapse
Kidney Wilms Tumor
Brain Cancer
Selumetinib + Vinblastine
for Low-Grade Glioma
This phase III trial investigates the best dose of vinblastine in combination with selumetinib and the benefit of adding vinblastine to selumetinib compared to selumetinib alone in treating children and young adults with low-grade glioma (a common type of brain cancer) that has come back after prior treatment (recurrent) or does not respond to therapy (progressive). Selumetinib is a drug that works by blocking a protein that lets tumor cells grow without stopping. Vinblastine blocks cell growth by stopping cell division and may kill cancer cells. Giving selumetinib in combination with vinblastine may work better than selumetinib alone in treating recurrent or progressive low-grade glioma.
Recruiting2 awards Phase 339 criteria
CBL0137
for Cancer
This trial tests CBL0137, a drug that blocks signals inside cancer cells, in patients whose solid tumors, including CNS tumors or lymphoma, have returned or not responded to treatment. By interfering with the cells' internal communication, the drug aims to stop their growth and cause them to die. CBL0137, also known as Curaxin, has shown antitumor activity in multiple cancers, including glioblastoma, renal cell carcinoma, melanoma, neuroblastoma, and small cell lung cancer.
Recruiting1 award Phase 1 & 213 criteria
Lower Radiotherapy Dose
for Brain Tumors
This phase II trial studies how well lower dose radiotherapy after chemotherapy (Carboplatin \& Etoposide) works in treating children with central nervous system (CNS) germinomas. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of tumor cells. Etoposide is in a class of medications known as podophyllotoxin derivatives. It blocks a certain enzyme needed for cell division and DNA repair and may kill cancer cells. Researchers want to see if lowering the dose of standard radiotherapy (RT) after chemotherapy can help get rid of CNS germinomas with fewer long-term side effects.
Recruiting1 award Phase 210 criteria
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Frequently asked questions
What kind of research happens at Children's Hospital of Orange County?
Children's Hospital of Orange County is a medical facility located in Orange, California. This center is recognized for care of T-Lymphoblastic Leukemia/Lymphoma, Uterine Tumors, Lymphoma, Brain Tumor, Acute Lymphoblastic Leukemia and other specialties. Children's Hospital of Orange County is involved with conducting 527 clinical trials across 828 conditions. There are 22 research doctors associated with this hospital, such as Elyssa M. Rubin, Mariko Sato, Josephine H. Haduong, and Raymond Wang, MD.
Where is Children's Hospital of Orange County located?
**Children's Hospital of Orange County (CHOC)**
Location: 1201 W. La Veta Ave., Orange, CA
For check-in, proceed to the Bill Holmes Tower entrance located on Pepper Street and follow the signs to the front entrance.
Who should I call to ask about financial aid or insurance network?
For assistance with questions on billing, our contact process involves the following steps:
1. For billing questions, contact the **Contact Process**:
- **Phone Call**: Our **Contact Process** involves the following steps:
- For billing questions, contact the **Contact Process**:
- **Phone Call**: Our **Phone Call** involves the process of contacting us via phone.
- **Phone Call**: Our **Phone Call** involves the process of contacting us via phone.
2. **Phone Call**: Our **Phone Call** involves the process of contacting us via phone.
3. **Phone Call**: Our **Phone Call** involves the process of contacting us via phone.
What insurance does Children's Hospital of Orange County accept?
The Children's Hospital of Orange County (CHOC) accepts a wide range of insurance plans, including most major PPO, HMO, and Medicare plans. They are contracted with various managed care organizations, including Aetna, Blue Cross of California, Blue Shield of California, Cigna Healthcare, HealthNet, and United HealthCare. For specific information about coverage or inquiries regarding specialist charges, it is recommended to contact your insurance carrier or the physician directly.
What awards or recognition has Children's Hospital of Orange County received?
Children's Hospital of Orange County (CHOC) in Orange, California, is a Level I pediatric trauma center, accredited by the American College of Surgeons (ACS) and Orange County Emergency Services. It has been designated as a Rare Disease Center of Excellence, focusing on novel cures for rare disorders. Additionally, CHOC has earned Magnet recognition for nursing excellence from the American Nurses Credentialing Center for the fourth time.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.