Search hospitals > California > Orange

Children's Hospital of Orange County

Claim this profile
Orange, California 92868
Global Leader in Cancer
Global Leader in Solid Tumors
Conducts research for Brain Tumor
Conducts research for Acute Lymphoblastic Leukemia
Conducts research for Leukemia
527 reported clinical trials
22 medical researchers
Photo of Children's Hospital of Orange County in OrangePhoto of Children's Hospital of Orange County in OrangePhoto of Children's Hospital of Orange County in Orange

Summary

Children's Hospital of Orange County is a medical facility located in Orange, California. This center is recognized for care of Cancer, Solid Tumors, Brain Tumor, Acute Lymphoblastic Leukemia, Leukemia and other specialties. Children's Hospital of Orange County is involved with conducting 527 clinical trials across 815 conditions. There are 22 research doctors associated with this hospital, such as Elyssa M. Rubin, Mariko Sato, Josephine H. Haduong, and Raymond Wang, MD.

Area of expertise

1Cancer
Global Leader
Children's Hospital of Orange County has run 74 trials for Cancer. Some of their research focus areas include:
Stage IV
Stage I
Stage II
2Solid Tumors
Global Leader
Children's Hospital of Orange County has run 72 trials for Solid Tumors. Some of their research focus areas include:
Stage IV
CTNNB1 positive
ROS1 positive

Top PIs

Clinical Trials running at Children's Hospital of Orange County

Brain Tumor
Leukemia
Testicular cancer
Cancer
Wilms Tumor
Neuroblastoma
Adrenoleukodystrophy
Burkitt Lymphoma
Brain Cancer
Acute Lymphoblastic Leukemia
Image of trial facility.

Selumetinib vs. Chemotherapy

for Brain Cancer

This trial is comparing a new drug, selumetinib, with standard chemotherapy to treat patients with a specific type of brain tumor. The patients do not have a certain genetic mutation and are not affected by a genetic disorder. Selumetinib works by blocking enzymes needed for tumor growth, while the standard drugs kill or stop tumor cells from dividing.
Recruiting2 awards Phase 3
Image of trial facility.

Selinexor + Radiation

for Brain Cancer

This trial tests the safety and effectiveness of combining selinexor with radiation therapy in children and young adults with aggressive brain tumors. Selinexor is a drug that blocks a protein to stop cancer cells from growing. The study aims to find the best dose and see if this combination can shrink tumors.
Recruiting1 award Phase 1 & 21 criteria
Image of trial facility.

Lower Radiotherapy Dose

for Brain Tumors

This phase II trial studies how well lower dose radiotherapy after chemotherapy (Carboplatin \& Etoposide) works in treating children with central nervous system (CNS) germinomas. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of tumor cells. Etoposide is in a class of medications known as podophyllotoxin derivatives. It blocks a certain enzyme needed for cell division and DNA repair and may kill cancer cells. Researchers want to see if lowering the dose of standard radiotherapy (RT) after chemotherapy can help get rid of CNS germinomas with fewer long-term side effects.
Recruiting1 award Phase 210 criteria

Similar Hospitals nearby

Frequently asked questions

What kind of research happens at Children's Hospital of Orange County?
Where is Children's Hospital of Orange County located?
Who should I call to ask about financial aid or insurance network?
What insurance does Children's Hospital of Orange County accept?
What awards or recognition has Children's Hospital of Orange County received?
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security