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Barbara Ann Karmanos Cancer Institute
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Detroit, Michigan 48201
Global Leader in Cancer
Global Leader in Lung Cancer
Conducts research for Breast Cancer
Conducts research for Pancreatic Cancer
Conducts research for Solid Tumors
1496 reported clinical trials
101 medical researchers
Summary
Barbara Ann Karmanos Cancer Institute is a medical facility located in Detroit, Michigan. This center is recognized for care of Cancer, Lung Cancer, Breast Cancer, Pancreatic Cancer, Solid Tumors and other specialties. Barbara Ann Karmanos Cancer Institute is involved with conducting 1,496 clinical trials across 903 conditions. There are 101 research doctors associated with this hospital, such as Ammar Sukari, Anthony F. Shields, Dipenkumar Modi, M.D., and Hirva Mamdani, MD.
Area of expertise
Cancer
Barbara Ann Karmanos Cancer Institute has run 243 trials for Cancer. Some of their research focus areas include:
Lung Cancer
Barbara Ann Karmanos Cancer Institute has run 214 trials for Lung Cancer. Some of their research focus areas include:
Top PIs
Ammar Sukari
Wayne State University/Karmanos Cancer Institute
3 years of reported clinical research
Anthony F. Shields
Barbara Ann Karmanos Cancer Institute
6 years of reported clinical research
Dipenkumar Modi, M.D.
Karmanos Cancer Institute
3 years of reported clinical research
Hirva Mamdani, MD
Karmanos Cancer Institute
6 years of reported clinical research
Clinical Trials running at Barbara Ann Karmanos Cancer Institute
Lung Cancer
Breast Cancer
Ovarian Cancer
Prostate Cancer
Pancreatic Cancer
Esophageal cancer
Breast cancer
Esophageal Cancer
Multiple Myeloma
Bladder Cancer
Neladalkib
for Non-Small Cell Lung Cancer
Multicenter, randomized, controlled, open-label, Phase 3 study designed to demonstrate that neladalkib (NVL-655) is superior to alectinib in prolonging progression-free survival (PFS) in patients with treatment-naïve, Anaplastic Lymphoma Kinase (ALK) positive, advanced Non-Small Cell Lung Cancer (NSCLC).
Recruiting
2 awards
Phase 3
4 criteria
Proton Craniospinal Radiation
for Cancer in the Brain and Spinal Cord
This phase III trial compares proton craniospinal irradiation (pCSI) to involved-field radiation therapy (IFRT) for the treatment of breast or non-small cell lung cancer that has spread from where it first started to the cerebrospinal fluid filled space that surrounds the brain and spinal cord (leptomeningeal metastasis). Patients with leptomeningeal metastasis (LM) may develop multiple areas of nervous system (neurologic) impairment that can be life-threatening. Radiation therapy (RT) effectively relieves local symptoms due to LM. RT uses high energy radiography (x-rays), particles, or radioactive seeds to kill cancer cells and shrink tumors. IFRT is commonly used to treat symptoms of LM. IFRT is radiation treatment that uses x-rays to treat specific areas of LM and to relieve and/or prevent symptoms. pCSI uses protons that can be directed with more accuracy than x-rays which allows treatment of the entire central nervous system space containing the cerebrospinal fluid (CSF), brain, and spinal cord. The pCSI treatment could delay the worsening of LM. Giving pCSI may be better than IFRT in treating LM in patients with breast or non-small cell lung cancer.
Recruiting
2 awards
Phase 3
3 criteria
Stereotactic Radiosurgery vs Whole-Brain Radiotherapy
for Brain Metastasis from Lung Cancer
This phase III trial compares the effect of stereotactic radiosurgery to standard of care memantine and whole brain radiation therapy that avoids the hippocampus (the memory zone of the brain) for the treatment of small cell lung cancer that has spread to the brain. Stereotactic radiosurgery is a specialized radiation therapy that delivers a single, high dose of radiation directly to the tumor and may cause less damage to normal tissue. Whole brain radiation therapy delivers a low dose of radiation to the entire brain including the normal brain tissue. Hippocampal avoidance during whole-brain radiation therapy (HA-WBRT) decreases the amount of radiation that is delivered to the hippocampus which is a brain structure that is important for memory. The drug, memantine, is also often given with whole brain radiotherapy because it may decrease the risk of side effects related to thinking and memory. Stereotactic radiosurgery may decrease side effects related to memory and thinking compared to standard of care HA-WBRT plus memantine.
Recruiting
2 awards
Phase 3
15 criteria
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Frequently asked questions
What kind of research happens at Barbara Ann Karmanos Cancer Institute?
Barbara Ann Karmanos Cancer Institute is a medical facility located in Detroit, Michigan. This center is recognized for care of Cancer, Lung Cancer, Breast Cancer, Pancreatic Cancer, Solid Tumors and other specialties. Barbara Ann Karmanos Cancer Institute is involved with conducting 1,496 clinical trials across 903 conditions. There are 101 research doctors associated with this hospital, such as Ammar Sukari, Anthony F. Shields, Dipenkumar Modi, M.D., and Hirva Mamdani, MD.
Where is Barbara Ann Karmanos Cancer Institute located?
The Barbara Ann Karmanos Cancer Institute, situated in midtown Detroit, MI at 4100 John R St, is the sole National Cancer Institute (NCI)-designated comprehensive cancer center in southeast Michigan. It stands among only 54 centers of its kind across the United States.
Who should I call to ask about financial aid or insurance network?
**Financial Assistance and Insurance Inquiries at Barbara Ann Karmanos Cancer Institute:** - For financial assistance, contact McLaren Patient Financial Services at (844) 321-1557 or submit the Financial Assistance Application to: McLaren Corporate Services, Attn: Revenue Cycle Operations, 50820 Schoenherr Rd., Shelby Township, MI 48315. - For insurance-related questions, call the hospital's general information line at 1-800-KARMANOS (1-800-527-6266).
What insurance does Barbara Ann Karmanos Cancer Institute accept?
The Barbara Ann Karmanos Cancer Institute accepts most health insurance plans, including Aetna, Blue Cross Blue Shield of MI, Cigna, Humana, Molina, and United Health Care among others. It is crucial to verify with your insurance provider about coverage for procedures at the Karmanos Cancer Institute before scheduling your first appointment. Patients are encouraged to review their insurance coverage annually to avoid unexpected bills.
What awards or recognition has Barbara Ann Karmanos Cancer Institute received?
The Barbara Ann Karmanos Cancer Institute, located in Detroit, Michigan, was awarded a $352,437 grant by the U CAN-CER VIVE Foundation in 2022 to support its research efforts. It has been recognized as a National Cancer Institute (NCI)-designated comprehensive cancer center since 1978, a testament to its scientific excellence and integrated research approaches in the fight against cancer.
Unbiased Results
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Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.