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nPEP (non-invasive positive expiratory pressure) mask for Tracheobronchomalacia

N/A
Waitlist Available
Led By Loretta G Que, MD
Research Sponsored by Duke University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, two weeks
Awards & highlights

Study Summary

This trial will test if a device that helps you breathe out can reduce coughing, help you breathe better, and improve quality of life for people with TBM who can't have stenting.

Eligible Conditions
  • Tracheobronchomalacia

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, two weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, two weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Cough Severity as Measured by the Cough Visual Analog Scale (VAS)
Change in Quality of Life as Measured by the Cough-Specific Quality-of-Life Questionnaire (CQLQ)
Change in Quality of Life as Measured by the Leicester Cough Questionnaire (LCQ)
Secondary outcome measures
Proximal Airway Reactance at 5 Hz (X5) as Assessed by Impulse Oscillometry

Trial Design

1Treatment groups
Experimental Treatment
Group I: nPEP RecipientsExperimental Treatment1 Intervention
Single-patient, adjustable expiratory resistance device that provides positive pressure (5 to 20 cm H2O) during expiration
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
nPEP (non-invasive positive expiratory pressure) mask
2021
N/A
~10

Find a Location

Who is running the clinical trial?

Duke UniversityLead Sponsor
2,358 Previous Clinical Trials
3,420,059 Total Patients Enrolled
Loretta G Que, MDPrincipal InvestigatorDuke University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
PEEP Mask for Tracheobronchomalacia-Induced Cough
2021. "PEEP Mask for Tracheobronchomalacia-Induced Cough". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04169282.
~3 spots leftby Apr 2025
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