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Optimization Strategies for Medication Use (MIDAS cRCT Trial)

N/A

Waitlist Available

Led By Jeremy B. Sussman, MD MS

Research Sponsored by VA Office of Research and Development

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline to 18-months

Awards & highlights

MIDAS cRCT Trial Summary

This trial will compare two approaches to changing how providers treat three common conditions in order to improve patient care.

Who is the study for?

This trial is for VA clinical settings with a team leader or champion, necessary resources, and service leadership buy-in. It aims to optimize treatment practices for overmedication, blood clots, abnormal heart rhythms, and insomnia. Individual patients are not being recruited; instead, entire clinics are the focus.Check my eligibility

What is being tested?

The MIDAS trial is testing two strategies: Academic Detailing (AD) and LEAP to improve medication use in VA healthcare systems. The goal is to reduce inappropriate medications, better manage blood thinners like DOACs in certain patients, and promote cognitive therapy over drugs for treating insomnia.See study design

What are the potential side effects?

Since this trial focuses on implementation strategies rather than direct patient interventions, it does not directly involve side effects of medications. However, improved practices may lead to reduced adverse drug reactions from overmedication or misuse.

MIDAS cRCT Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline to 18-months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline to 18-months

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline to 18-months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Monthly facility percent of inappropriate medication use

Secondary outcome measures

Change in mean cognitive behavioral therapy for insomnia (CBTI) sessions completed

Change in monthly medication costs for all drugs

Change in number of inappropriate medications at a patient-level

+5 more

Other outcome measures

Change in Best Places to Work Score

Change in Employee Burnout

Change in Employee Engagement in Quality Improvement

+1 more

MIDAS cRCT Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: AD + LEAP CombinedExperimental Treatment2 Interventions

This arm combines use of AD plus the Learn. Engage. Act. Process (LEAP) program. LEAP is a 6-month quality improvement coaching program plus a 6-month monthly follow-up.

Group II: Academic Detailing (AD) OnlyActive Control1 Intervention

One-on-one educational outreach to employees and providers.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

LEAP

2016

N/A

~74250

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

VA Office of Research and DevelopmentLead Sponsor

1,609 Previous Clinical Trials

3,306,429 Total Patients Enrolled

Jeremy B. Sussman, MD MSPrincipal InvestigatorVA Ann Arbor Healthcare System, Ann Arbor, MI

2 Previous Clinical Trials

47 Total Patients Enrolled

Jacob E Kurlander, MD MS MSPrincipal InvestigatorVA Ann Arbor Healthcare System, Ann Arbor, MI

1 Previous Clinical Trials

4 Total Patients Enrolled

Media Library

LEAP Clinical Trial Eligibility Overview. Trial Name: NCT05065502 — N/A

Overmedication Research Study Groups: AD + LEAP Combined, Academic Detailing (AD) Only

Overmedication Clinical Trial 2023: LEAP Highlights & Side Effects. Trial Name: NCT05065502 — N/A

LEAP 2023 Treatment Timeline for Medical Study. Trial Name: NCT05065502 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is enrolment currently open for this experiment?

"Affirmative, the information on clinicaltrials.gov states that this medical investigation is currently in search of subjects. The study was initiated on May 3rd 2021 and it's most recent update came July 18th 2022. 24 patients need to be enlisted from one site only."

Answered by AI

How extensive is the sample size for this research endeavor?

"Affirmative, the information hosted on clinicaltrials.gov confirms that this trial is actively looking for new members; it was first posted in May 2021 and updated most recently in July 2022. They need 24 volunteers to be recruited from one site."

Answered by AI