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Behavioural Intervention

tDCS for Post-Stroke Fatigue

N/A

Waitlist Available

Led By John H Kindred, Ph.D.

Research Sponsored by Medical University of South Carolina

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Aged 35-80 years

Able to walk 10m unassisted

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, post-intervention (2-weeks)

Awards & highlights

Study Summary

This trial will investigate whether transcranial direct current stimulation (tDCS) can help improve fatigue and inflammation after a stroke.

Who is the study for?

This trial is for individuals aged 35-80 who can walk on their own and have experienced fatigue for at least 6 months following a stroke. It's not suitable for those with multiple strokes in different brain hemispheres, other neurological conditions like MS or Parkinson's, severe high blood pressure, certain types of strokes, metal implants that interfere with MRI/TMS/tDCS, or ongoing depression/anxiety disorders.Check my eligibility

What is being tested?

The study is testing the effects of anodal transcranial direct current stimulation (a-tDCS), which delivers small electrical currents to the brain to see if it can reduce post-stroke fatigue and inflammation compared to sham (fake) stimulation.See study design

What are the potential side effects?

tDCS may cause mild side effects such as itching, tingling, or discomfort at the electrode site. More serious risks include headache, nausea, or dizziness but these are rare. The sham treatment has no active components so any side effects would be minimal.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am between 35 and 80 years old.

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I can walk 10 meters by myself.

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I have been feeling tired for the last 6 months.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, post-intervention (2-weeks)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, post-intervention (2-weeks)

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, post-intervention (2-weeks) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Fatigue Severity Scale (FSS) score

Secondary outcome measures

Change in Fatigue Assessment Scale (FAS)

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: RealExperimental Treatment1 Intervention

Randomly selected participants will receive 20 min. of anodal transcranial direct current stimulation to the the top of their heads. The current will slowly be ramped up over 30 secs.

Group II: ShamPlacebo Group1 Intervention

Randomly selected participants will receive 20 min. of sham transcranial direct current stimulation to the top of their heads. Sham stimulation is accomplished by turning on the device and slowly increasing and subsequently decreasing the amount of current to zero. This occurs over 30 secs.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

anodal transcranial direct current stimulation (a-tDCS)

2022

N/A

~20

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)NIH

1,964 Previous Clinical Trials

2,674,718 Total Patients Enrolled

79 Trials studying Stroke

5,375 Patients Enrolled for Stroke

National Center of Neuromodulation for RehabilitationOTHER

10 Previous Clinical Trials

219 Total Patients Enrolled

4 Trials studying Stroke

97 Patients Enrolled for Stroke

Medical University of South CarolinaLead Sponsor

933 Previous Clinical Trials

7,394,603 Total Patients Enrolled

67 Trials studying Stroke

60,039 Patients Enrolled for Stroke

Media Library

Transcranial Direct Current Stimulation (tDCS) (Behavioural Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05330988 — N/A

Stroke Research Study Groups: Real, Sham

Stroke Clinical Trial 2023: Transcranial Direct Current Stimulation (tDCS) Highlights & Side Effects. Trial Name: NCT05330988 — N/A

Transcranial Direct Current Stimulation (tDCS) (Behavioural Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05330988 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are individuals still being sought to participate in this research?

"This clinical trial, initially posted on the 12th of July and updated as recently as the 25th, is actively searching for eligible participants. Clinicaltrials.gov has all relevant information available to interested parties."

Answered by AI

Who meets the qualifications necessary to participate in this clinical trial?

"The researchers are seeking a cohort of 24 stroke survivors aged between 35 and 80 years old. Prerequisites for enrolment include: male or female, any ethnicity, post-stroke 6+ months prior to screening, presence of fatigue symptoms over the past half year, able to walk 10 meters unassisted."

Answered by AI

Does this medical study accept participants who are 40 and above?

"This clinical study is searching for test subjects aged between 35 and 80."

Answered by AI

What is the size of the participant pool for this clinical evaluation?

"Affirmative, the information on clinicaltrials.gov indicates that this trial is currently enrolling subjects. This research project was first available to prospective patients on July 12th 2022 and has been amended most recently on July 25th 2022. The 24 participants required must be sourced from only 1 medical facility."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Post-stroke Fatigue, Inflammation, tDCS

John H Kindred 2022. "Post-stroke Fatigue, Inflammation, tDCS". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05330988.