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day 3 uterine transfer for Infertility (PRECiSE Trial)

N/A
Waitlist Available
Led By Werner Neuhausser, MD PhD
Research Sponsored by Beth Israel Deaconess Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years
Awards & highlights

PRECiSE Trial Summary

This trial is testing whether it's better to transfer embryos on day 3 or day 5 of IVF in patients with 5 or fewer embryos. The goal is to find the best way to maximize the chances of success for these patients.

PRECiSE Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
live birth
Secondary outcome measures
Clinical pregnancy
Multiple pregnancy
Ongoing pregnancy
+1 more

PRECiSE Trial Design

2Treatment groups
Experimental Treatment
Group I: day 5 embryo transferExperimental Treatment1 Intervention
embryo transfer 5 days after fertilization
Group II: day 3 embryo transferExperimental Treatment1 Intervention
embryo transfer 3 days after fertilization
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
day 3 uterine transfer
2021
N/A
~10
day 5 uterine transfer
2021
N/A
~10

Find a Location

Who is running the clinical trial?

Beth Israel Deaconess Medical CenterLead Sponsor
836 Previous Clinical Trials
13,010,326 Total Patients Enrolled
Boston IVFOTHER
19 Previous Clinical Trials
20,214 Total Patients Enrolled
18 Trials studying Infertility
19,914 Patients Enrolled for Infertility
Werner Neuhausser, MD PhDPrincipal Investigator - Beth Israel Deaconess Medical Center
Beth Israel Deaconess Medical Center

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is it possible to sign up for participation in this research endeavor?

"Per clinicaltrials.gov, this experiment is actively enrolling participants at the time of writing. It was originally posted on March 1st 2021 and updated as recently as 6th day of that same month."

Answered by AI

What criteria must participants meet to qualify for this investigation?

"This clinical trial necessitates that applicants have infertility and be between 18-44 years old. The study aims to enrol 658 volunteers in total."

Answered by AI

Is the age criteria for this clinical experiment inclusive of people over 45?

"As dictated by the eligibility requirements, individuals between 18 and 44 years old are permitted to partake in this research."

Answered by AI

To what extent is enrollment available for this research project?

"Affirmative, the information on clinicaltrials.gov affirms this medical trial is presently in search of participants. This study was first advertised on March 1st 2021 and has been recently modified as of June 3rd 2021 with a requirement for 658 patients from one clinic location."

Answered by AI

Who else is applying?

What state do they live in?
Florida
Ohio
Texas
Other
How old are they?
18 - 65
What site did they apply to?
Boston IVF
What portion of applicants met pre-screening criteria?
Met criteria
Recent research and studies
Fertility and SterilityJournal
Introduction of Blastocyst Culture and Transfer for All Patients in an in Vitro Fertilization Program
Marek, Del, Martin Langley, David K Gardner, Nils Confer, Kathleen M Doody, and Kevin J Doody. 1999. “Introduction of Blastocyst Culture and Transfer for All Patients in an in Vitro Fertilization Program”. Fertility and Sterility. Elsevier BV. doi:10.1016/s0015-0282(99)00409-4.
Human ReproductionJournal
Blastocyst Stage Transfer: Pitfalls and Benefits. Too Soon to Abandon Current Practice?
Tsirigotis, M.. 1998. “Blastocyst Stage Transfer: Pitfalls and Benefits. Too Soon to Abandon Current Practice?”. Human Reproduction. Oxford University Press (OUP). doi:10.1093/humrep/13.12.3285.
Reproductive HealthJournal
Non-inferiority of Cleavage-stage Versus Blastocyst-stage Embryo Transfer in Poor Prognosis IVF Patients (precise Trial): Study Protocol for a Randomized Controlled Trial
Neuhausser, Werner M., Denis A. Vaughan, Denny Sakkas, Michele R. Hacker, Tom Toth, and Alan Penzias. 2020. “Non-inferiority of Cleavage-stage Versus Blastocyst-stage Embryo Transfer in Poor Prognosis IVF Patients (precise Trial): Study Protocol for a Randomized Controlled Trial”. Reproductive Health. Springer Science and Business Media LLC. doi:10.1186/s12978-020-0870-y.
Fertility and SterilityJournal
Blastocyst Culture and Transfer in Clinical-assisted Reproduction: A Committee Opinion
“Blastocyst Culture and Transfer in Clinical-assisted Reproduction: A Committee Opinion”. 2013. “Blastocyst Culture and Transfer in Clinical-assisted Reproduction: A Committee Opinion”. Fertility and Sterility. Elsevier BV. doi:10.1016/j.fertnstert.2013.01.087.
~2 spots leftby Apr 2025
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