National Diabetes Prevention Program for Obesity

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Denver Health, Denver, CO
Obesity+4 More
National Diabetes Prevention Program - Behavioral
Eligibility
18+
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether a pre-session can increase attendance and weight loss in people with diabetes.

See full description

Eligible Conditions

  • Obesity
  • Gestational Diabetes Mellitus (GDM)
  • Prediabetic State

Treatment Effectiveness

Study Objectives

This trial is evaluating whether National Diabetes Prevention Program will improve 1 primary outcome and 1 secondary outcome in patients with Obesity. Measurement will happen over the course of 12 months.

12 months
Attendance
Weight loss

Trial Safety

Trial Design

2 Treatment Groups

Usual care NDPP
1 of 2
Pre-NDPP
1 of 2
Active Control
Experimental Treatment

This trial requires 500 total participants across 2 different treatment groups

This trial involves 2 different treatments. National Diabetes Prevention Program is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Pre-NDPPPresessions + usual care NDPP
Usual care NDPP
Behavioral
Usual care NDPP only

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 12 months
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 12 months for reporting.

Closest Location

Denver Health - Denver, CO

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 3 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Denver Health patients
BMI≥25 (≥23 if Asian)
History of recent prediabetes or former gestational diabetes (GDM) diagnosis (patients without known prediabetes or past GDM may also be eligible based on a risk screening tool)

Patient Q&A Section

What is prediabetic state?

"About 5% of males had prediabetic or diabetes diagnoses, with one third of the affected males having at least one risk factor for diabetes. Males with diabetes have a higher fat mass which is not compensated by lean body mass and therefore are more susceptible to diabetes complications like peripheral or coronary artery disease." - Anonymous Online Contributor

Unverified Answer

How many people get prediabetic state a year in the United States?

"Estimates of prediabetic state (≥6.1 kg/m(2)) are likely to change over time because of differences between epidemiology and surveillance surveys. We discuss the implications for predicting prediabetes and the potential impact on health care expenditures for prediabetic state." - Anonymous Online Contributor

Unverified Answer

What causes prediabetic state?

"There is strong evidence that the occurrence and the extent of coronary heart disease in men vary widely from person to person and from place to place. This evidence is not consistent with the hypothesis that risk factors in men explain the great heterogeneity in coronary heart disease rates. However, risk factors in men may play a role in the genesis of coronary heart disease. We recommend systematic efforts to discover the underlying causes of coronary heart disease in men." - Anonymous Online Contributor

Unverified Answer

What are common treatments for prediabetic state?

"There is a higher percentage of patients who are obese when compared to other populations, and this could be of great importance in terms of complications. Some people in this group may also be prone to developing diabetes, and some of the complications may be related to insulin resistance. It is a real possibility, and some of the medications for other conditions could be helpful in this aspect." - Anonymous Online Contributor

Unverified Answer

What are the signs of prediabetic state?

"The signs of prediabetic state are present in one out of three patients who are otherwise asymptomatic. The first clinical manifestation of prediabetes is overt diabetes mellitus in 0.6% of patients; the first clinical manifestation of diabetes in nondiabetics is stroke in 0.3% of patients. The early recognition and management of prediabetics is essential to prevent complications from diabetes." - Anonymous Online Contributor

Unverified Answer

Can prediabetic state be cured?

"At least in the short term, a state of prediabetes has a great impact on cardiovascular risk and quality of life and has profound adverse effects on the quality of life and the rate of diabetes onset in young and middle-aged people." - Anonymous Online Contributor

Unverified Answer

Has national diabetes prevention program proven to be more effective than a placebo?

"Compared with a placebo, diet alone was more effective in achieving HbA1c values of 6.0% and less risk factors and in achieving better clinical outcomes." - Anonymous Online Contributor

Unverified Answer

Does national diabetes prevention program improve quality of life for those with prediabetic state?

"The national DPP did not improve QOL for patients who had a pre-DM, compared with patients who did not receive DPP. More researches are needed to clarify whether this result was due to the DPP or to the pre-DM itself." - Anonymous Online Contributor

Unverified Answer

Have there been other clinical trials involving national diabetes prevention program?

"The national diabetes prevention programme provided an optimal clinical environment for diabetes prevention research, with the potential to yield useful information for diabetes management practice. Further studies, especially long-term studies, are required to verify these findings." - Anonymous Online Contributor

Unverified Answer

What are the common side effects of national diabetes prevention program?

"The national DPP and its strategies contribute to improved diabetes prevention. The present review provides a comprehensive overview of the common side effects of the DPP, which will be helpful to the national implementation team and will provide a reference for other countries to develop national prevention programs." - Anonymous Online Contributor

Unverified Answer

Is national diabetes prevention program safe for people?

"There were some risks to the overall well-being of the people participating in the national DPP and the DPP is not recommended as a public health strategy. There were no deaths from DPP interventions." - Anonymous Online Contributor

Unverified Answer

Is national diabetes prevention program typically used in combination with any other treatments?

"Recent findings does not demonstrate any evidence that a NPDP is used in combination with other non-surgical treatment to prevent T2DM, even in countries that have a high prevalence of diabetes. This is possibly because these NPDPs have not been tested, used or implemented in those countries." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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