Differentiated Box for Malignant Neoplasm of Colon

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Penn Medicine, Philadelphia, PA
Malignant Neoplasm of Colon+3 More
Differentiated Box - Behavioral
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This project aims to evaluate different approaches to increase colorectal cancer screening among primary care patients at Penn Medicine through a centralized screening outreach program. In a pragmatic trial, we will evaluate different approaches to increase response rate to mailed fecal immunochemical test (FIT) kits among eligible patients, including differentiated packaging, sending text reminders, and personalized reminders.

Eligible Conditions

  • Malignant Neoplasm of Colon
  • Colorectal Carcinoma

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Malignant Neoplasm of Colon

Study Objectives

0 Primary · 4 Secondary · Reporting Duration: 6 months

6 months
Colorectal Cancer (CRC) Screening Completion (any)
FIT Completion
FIT Positive Follow-up Completion
FIT Positive Follow-up Scheduling

Trial Safety

Safety Progress

1 of 3

Other trials for Malignant Neoplasm of Colon

Trial Design

16 Treatment Groups

Arm 8: Standard Mail + No Text + No Reminder
1 of 16
Arm 7: Standard Mail + No Text + Reminder
1 of 16
Arm 4: Box + No Text + No Reminder
1 of 16
Arm 8
1 of 16
Arm 6
1 of 16
Arm 3: Box + No Text + Reminder
1 of 16
Arm 1
1 of 16
Arm 2
1 of 16
Arm 3
1 of 16
Arm 7
1 of 16
Arm 2: Box + Text + No Reminder
1 of 16
Arm 6: Standard Mail + Text + No Reminder
1 of 16
Arm 5: Standard Mail + Text + Reminder
1 of 16
Arm 4
1 of 16
Arm 5
1 of 16
Arm 1: Box + Text + Reminder
1 of 16
Experimental Treatment

5460 Total Participants · 16 Treatment Groups

Primary Treatment: Differentiated Box · No Placebo Group · N/A

Arm 8: Standard Mail + No Text + No ReminderExperimental Group · 3 Interventions: No Text, No Reminder, Standard Mail · Intervention Types: Behavioral, Behavioral, Behavioral
Arm 7: Standard Mail + No Text + ReminderExperimental Group · 3 Interventions: No Text, Reminder, Standard Mail · Intervention Types: Behavioral, Behavioral, Behavioral
Arm 4: Box + No Text + No ReminderExperimental Group · 3 Interventions: Differentiated Box, No Text, No Reminder · Intervention Types: Behavioral, Behavioral, Behavioral
Arm 8Experimental Group · 3 Interventions: No Text, No Reminder, Standard Mail · Intervention Types: Behavioral, Behavioral, Behavioral
Arm 6Experimental Group · 3 Interventions: Text, No Reminder, Standard Mail · Intervention Types: Behavioral, Behavioral, Behavioral
Arm 3: Box + No Text + ReminderExperimental Group · 3 Interventions: Differentiated Box, No Text, Reminder · Intervention Types: Behavioral, Behavioral, Behavioral
Arm 1Experimental Group · 3 Interventions: Differentiated Box, Text, Reminder · Intervention Types: Behavioral, Behavioral, Behavioral
Arm 2Experimental Group · 3 Interventions: Differentiated Box, Text, No Reminder · Intervention Types: Behavioral, Behavioral, Behavioral
Arm 3Experimental Group · 3 Interventions: Differentiated Box, No Text, Reminder · Intervention Types: Behavioral, Behavioral, Behavioral
Arm 7Experimental Group · 3 Interventions: No Text, Reminder, Standard Mail · Intervention Types: Behavioral, Behavioral, Behavioral
Arm 2: Box + Text + No ReminderExperimental Group · 3 Interventions: Differentiated Box, Text, No Reminder · Intervention Types: Behavioral, Behavioral, Behavioral
Arm 6: Standard Mail + Text + No ReminderExperimental Group · 3 Interventions: Text, No Reminder, Standard Mail · Intervention Types: Behavioral, Behavioral, Behavioral
Arm 5: Standard Mail + Text + ReminderExperimental Group · 3 Interventions: Text, Reminder, Standard Mail · Intervention Types: Behavioral, Behavioral, Behavioral
Arm 4Experimental Group · 3 Interventions: Differentiated Box, No Text, No Reminder · Intervention Types: Behavioral, Behavioral, Behavioral
Arm 5Experimental Group · 3 Interventions: Text, Reminder, Standard Mail · Intervention Types: Behavioral, Behavioral, Behavioral
Arm 1: Box + Text + ReminderExperimental Group · 3 Interventions: Differentiated Box, Text, Reminder · Intervention Types: Behavioral, Behavioral, Behavioral
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Text
2022
N/A
~40
Reminder
2014
N/A
~207520

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 6 months
Closest Location: Penn Medicine · Philadelphia, PA
Photo of Philadelphia 1Photo of Philadelphia 2Photo of Philadelphia 3
2019First Recorded Clinical Trial
1 TrialsResearching Malignant Neoplasm of Colon
12 CompletedClinical Trials

Who is running the clinical trial?

Abramson Cancer Center of the University of PennsylvaniaLead Sponsor
345 Previous Clinical Trials
79,022 Total Patients Enrolled
1 Trials studying Malignant Neoplasm of Colon
50 Patients Enrolled for Malignant Neoplasm of Colon
Shivan Mehta, MDPrincipal InvestigatorUniversity of Pennsylvania
14 Previous Clinical Trials
52,310 Total Patients Enrolled
1 Trials studying Malignant Neoplasm of Colon
440 Patients Enrolled for Malignant Neoplasm of Colon

Eligibility Criteria

Age 18+ · All Participants · 3 Total Inclusion Criteria

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About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.