PBI Radiotherapy for Breast Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
The purpose of this study is to test whether a radiotherapy regimen of 8 GY x 3 days over 5 days (every other day) is as safe (well-tolerated) and effective as 6 Gy x 5 over five consecutive days
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Is PBI Radiotherapy safe for breast cancer patients?
Research shows that PBI Radiotherapy is generally safe for breast cancer patients, with studies reporting mild long-term side effects and low immediate toxicity. Most patients experience minimal acute side effects, and the treatment is considered feasible and safe for selected early breast cancer cases.12345
How does PBI Radiotherapy differ from other breast cancer treatments?
PBI Radiotherapy is unique because it targets only the tumor bed with high doses of radiation, unlike traditional whole-breast irradiation that treats the entire breast. This approach can reduce treatment time and potentially minimize side effects, making it a promising option for patients with early-stage breast cancer.13678
What data supports the effectiveness of the treatment PBI Radiotherapy for Breast Cancer?
Who Is on the Research Team?
Naamit K Gerber, MD
Principal Investigator
NYU Langone Medical Center
Are You a Good Fit for This Trial?
This trial is for post-menopausal women with a specific early-stage breast cancer (pT1), who have had the tumor surgically removed with clear margins and no spread to lymph nodes. Women must not have had previous radiation on the same breast or a high proportion of DCIS, which suggests extensive intraductal component.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Radiation
Participants receive prone partial breast irradiation with either 8 Gy x 3 over 5 days or 6 Gy x 5 over 5 days
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- PBI Radiotherapy 6 Gy
- PBI Radiotherapy 8 Gy
Find a Clinic Near You
Who Is Running the Clinical Trial?
NYU Langone Health
Lead Sponsor