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Belzutifan for Kidney Cancer
Study Summary
This trial will test if belzutifan can shrink tumors in people with von Hippel-Lindau disease-related kidney cancer.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I have a measurable kidney cancer tumor that doesn't need immediate surgery.My scans show cancer has spread to other parts of my body.I have been diagnosed with von Hippel Lindau disease.I have been treated with belzutifan or a similar drug before.I have received treatments targeting cancer growth.I need surgery soon for my cancer.
- Group 1: Open Label Belzutifan
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is this research still recruiting patients to participate?
"No, this study is not actively recruiting participants. The clinical trial was originally posted on 5/2/2018 and last updated on 11/1/2022. There are 4128 other clinical trials currently accepting participants at this time."
Is this the initial study of its kind to be conducted on humans?
"There are currently 16 ongoing trials for the use of Belzutifan globally. The first trial was conducted in 2016 and, although it has only been 5 years since the initial study, 1 additional trial has already been completed."
Are there any known adverse effects of Belzutifan?
"Belzutifan's score is a 2. This means that while there is some evidence supporting its safety, none of the available data suggests that it is an effective medication."
How many different research institutions are participating in this study?
"NIH Clinical Center in Bethesda, MD, Huntsman Cancer Institute in Salt Lake City, UT, and University of Pennsylvania Medical Center in Philadelphia are some of the places where this trial is enrolling patients. There are also 8 other sites."
Do we have any prior experience with Belzutifan?
"16 different clinical trials for Belzutifan are ongoing, with 3 of those in Phase 3. The majority of these studies originate from Omaha, Nebraska, but there are 849 research sites total conducting investigations into Belzutifan."
What are the common indications for Belzutifan?
"Belzutifan can be used to ameliorate the symptoms of malignant neoplasms, anemia, sickle cell, and von hippel lindau disease."
How many test subjects are a part of this research?
"As of right now, this clinical trial has no open positions. However, it is important to note that the date range for this study was from May 2nd, 2018 to November 1st, 2022. If you are looking for other trials enrolling participants with carcinoma or renal cell, there are 4112 and 16 studies respectively that may have open positions."
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