22 Participants Needed

nTMS for Brain Metastasis Planning

CC
Overseen ByCaroline Chung
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: M.D. Anderson Cancer Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Approved in 6 JurisdictionsThis treatment is already approved in other countries

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial studies how well nTMS works in planning radiation therapy for patients with brain metastases in the motor cortex. nTMS maps brain areas that control muscles, helping doctors avoid damaging these critical areas during treatment. This could lead to safer and more effective radiation therapy. nTMS has been widely used for planning in brain tumor surgeries to map important areas and improve patient outcomes.

Who Is on the Research Team?

Caroline Chung | MD Anderson Cancer Center

Caroline Chung

Principal Investigator

M.D. Anderson Cancer Center

Are You a Good Fit for This Trial?

This trial is for adults with brain metastases in the motor cortex who've had stereotactic radiosurgery (SRS) 3-18 months prior. Participants must be able to undergo nTMS and EMG, have used MRI for SRS planning, and complete questionnaires in English. Excluded are those with significant cognitive/psychiatric issues or poor physical status that prevents participation.

Inclusion Criteria

I have brain cancer near the motor cortex and had radiation therapy 3-18 months ago.
I can complete health questionnaires in English.
You must be able to take part in tests that stimulate both sides of your brain's motor areas.
See 2 more

Exclusion Criteria

I can complete physical exams and answer questions without cognitive or psychiatric issues.
I struggle with daily activities due to my health condition.
I have not had treatments that affect my thinking, mood, or movement.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Diagnostic

Patients undergo nTMS and perform tasks testing grip and pinch strength

1 hour
1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after diagnostic procedures

Up to 1 year

What Are the Treatments Tested in This Trial?

Interventions

  • Navigated Transcranial Magnetic Stimulation
  • Stereotactic Radiosurgery
Trial Overview The study tests how well nTMS aids in planning stereotactic radiosurgery for patients with brain tumors affecting muscle control. It aims to map out areas of the brain responsible for movement to determine safe radiation levels without harming these critical regions.
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: Diagnostic (nTMS, sensory testing)Experimental Treatment4 Interventions

Stereotactic Radiosurgery is already approved in European Union, United States, Canada, Japan, China, Switzerland for the following indications:

πŸ‡ͺπŸ‡Ί
Approved in European Union as Stereotactic Radiosurgery for:
πŸ‡ΊπŸ‡Έ
Approved in United States as Stereotactic Radiosurgery for:
πŸ‡¨πŸ‡¦
Approved in Canada as Stereotactic Radiosurgery for:
πŸ‡―πŸ‡΅
Approved in Japan as Stereotactic Radiosurgery for:
πŸ‡¨πŸ‡³
Approved in China as Stereotactic Radiosurgery for:
πŸ‡¨πŸ‡­
Approved in Switzerland as Stereotactic Radiosurgery for:

Find a Clinic Near You

Who Is Running the Clinical Trial?

M.D. Anderson Cancer Center

Lead Sponsor

Trials
3,107
Recruited
1,813,000+

National Cancer Institute (NCI)

Collaborator

Trials
14,080
Recruited
41,180,000+
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top
Terms of ServiceΒ·Privacy PolicyΒ·CookiesΒ·Security