CLUE intervention (EMA + EMI) for Generalized Anxiety Disorder

Phase-Based Progress Estimates
Ohio University, Athens, OHGeneralized Anxiety Disorder+1 More14 days of EMI - Behavioral
All Sexes
What conditions do you have?

Study Summary

This trial is testing whether two different types of interventions can help reduce symptoms of anxiety in adults.

Eligible Conditions
  • Emotional Disorder
  • Generalized Anxiety Disorder

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

2 Primary · 18 Secondary · Reporting Duration: One month follow up

14-day EMA/EMI
Feasibility of service
14-day EMA/EMI period
EMA questions
One month follow up
Alcohol Use Disorder Identification Test (AUDIT)
COVID-19 contraction questions
COVID-19 impact battery short-form (CIB-SF)
Client Satisfaction Questionnaire-8
Drug Use Disorders Identification Test (DUDIT)
Firearm ownership
Insomnia Severity Index (ISI)
Intolerance of Uncertainty-12
Oxford Covid-19 Vaccine Hesitancy Scale
PROMIS anxiety scale
PROMIS depression scale
PROMIS stress scale
Penn State Worry Questionnaire (PSWQ)
Perseverative Thought Questionnaire (PTQ)
Positive and Negative Affect Schedule-SF
Ruminative Response Scale (RRS)
The Anxiety Depression Distress Inventory-27 (ADDI-27)
The Metacognition Questionnaire-30 (MCQ)

Trial Safety

Safety Progress

1 of 3

Trial Design

3 Treatment Groups

CLUE intervention (EMA + EMI)
1 of 3
CLUE intervention (EMA only)
1 of 3
Waitlist control
1 of 3

Active Control

45 Total Participants · 3 Treatment Groups

Primary Treatment: CLUE intervention (EMA + EMI) · No Placebo Group · N/A

CLUE intervention (EMA + EMI)ActiveComparator Group · 2 Interventions: 14 days of EMI, Uncertainty reappraisal training · Intervention Types: Behavioral, Behavioral
CLUE intervention (EMA only)
ActiveComparator Group · 1 Intervention: Uncertainty reappraisal training · Intervention Types: Behavioral
Waitlist controlNoIntervention Group · 1 Intervention: Waitlist control · Intervention Types:

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: one month follow up

Who is running the clinical trial?

Ohio UniversityLead Sponsor
65 Previous Clinical Trials
36,885 Total Patients Enrolled

Eligibility Criteria

Age 18+ · All Participants · 3 Total Inclusion Criteria

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Frequently Asked Questions

Are participants currently welcome to join this experiment?

"Affirmative. According to information provided on, the trial is currently enrolling patients and has been since its launch date of September 15th 2021. The last modification was made December 13th 2021 and 45 individuals are needed from a single site for participation in this medical study." - Anonymous Online Contributor

Unverified Answer

What goals are investigators attempting to accomplish with this clinical trial?

"The primary aim of the survey, which will be measured over a one-month follow up period is to evaluate service feasibility. There are also three secondary objectives that include assessing Ruminative Response Scale (RRS), Intolerance of Uncertainty-12 (IU-12), and PROMIS Anxiety scale scores. The RRS comprises queries regarding responses to depressed mood, IU-12 evaluates an individual's aptitude for tolerating ambiguous situations, while the PROMIS Anxiety scale measures fear and somatic symptoms in greater detail." - Anonymous Online Contributor

Unverified Answer

What is the current capacity for participants in this research trial?

"Affirmative. verifies that the trial, which was initiated on September 15th 2021, is currently recruiting participants from a single site and needs 45 volunteers to complete it." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.