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2% Lidocaine HCl topical solution for Postoperative Nausea and Vomiting

Phase 4
Waitlist Available
Led By Marc Royo, MD
Research Sponsored by Milton S. Hershey Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up at 6 hours after surgery or discharge home, whichever occurs first
Awards & highlights

Study Summary

This trial is testing whether intranasal lidocaine can prevent postoperative nausea and vomiting (PONV).

Eligible Conditions
  • Postoperative Nausea and Vomiting

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~at 6 hours after surgery or discharge home, whichever occurs first
This trial's timeline: 3 weeks for screening, Varies for treatment, and at 6 hours after surgery or discharge home, whichever occurs first for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Incidence
Secondary outcome measures
Duration of nausea and/or vomiting
Duration of stay in PACU.
Intensity
+3 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: test drugExperimental Treatment1 Intervention
2% Lidocaine
Group II: PlaceboPlacebo Group1 Intervention
0.9% Normal Saline

Find a Location

Who is running the clinical trial?

Milton S. Hershey Medical CenterLead Sponsor
494 Previous Clinical Trials
2,798,842 Total Patients Enrolled
2 Trials studying Postoperative Nausea and Vomiting
200 Patients Enrolled for Postoperative Nausea and Vomiting
Marc Royo, MDPrincipal InvestigatorPenn State Health

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What medical issues does a 2% Lidocaine HCl topical solution usually address?

"A 2% Lidocaine HCl topical solution can be applied to treat a range of conditions, such as raised intra ocular pressure (iop), nasal discomfort, and the over-production of dangerous substances in the kidneys."

Answered by AI

What is the size of this research endeavor's participant population?

"Unfortunately, recruitment for this trial has closed as of April 6th 2022. However, if you are looking to join a medical study there are still 115 trials actively searching for participants with postoperative nausea and 211 studies recruiting patients who need 2% Lidocaine HCl topical solution."

Answered by AI

Are there any additional research initiatives that have focused upon the use of 2% Lidocaine HCl topical solution?

"Presently, 211 clinical trials are being conducted pertaining to the efficacy of 2% Lidocaine HCl topical solution. Out of these active studies, 53 have reached Phase 3 testing. The preponderance of research for this treatment is centered in Duarte, California; however there are 1,461 different sites running experiments across the globe."

Answered by AI

Is enrollment in this medical trial still ongoing?

"At this moment, clinicaltrials.gov does not list the trial as actively recruiting participants. This experiment was initially posted in October 2022 and revised last April yet is currently dormant; however, there are 326 other research trials searching for volunteers at present."

Answered by AI

Has the FDA sanctioned 2% Lidocaine HCl topical solution?

"There is ample evidence for the safety of 2% Lidocaine HCl topical solution, thus receiving a score of 3 on our evaluation scale. This compound has been approved by the FDA and is currently in Phase 4 trials."

Answered by AI
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~0 spots leftby Apr 2025