Shockwave Therapy for Erectile Dysfunction

Not currently recruiting at 2 trial locations
BR
MJ
Overseen ByMonica Johnson, RN
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests low-intensity acoustic shockwave therapy to determine its effectiveness in improving erectile dysfunction by enhancing blood flow and sexual function. The focus is on men with increased firmness in the penis, which might be reversible with this treatment. Sexually active men diagnosed with erectile dysfunction may be suitable candidates for this study. As an unphased trial, participants can contribute to innovative research that could lead to new treatment options.

Will I have to stop taking my current medications?

If you are using medications for erectile dysfunction, like PDE5 inhibitors or penile injection therapy, you need to stop them at least two weeks before the first visit. Other medications are not mentioned, so it's best to discuss with the study team.

What prior data suggests that this device is safe for treating erectile dysfunction?

Research has shown that low-intensity shockwave therapy (LiST) for erectile dysfunction is generally easy for patients to handle. Most studies find that patients do not experience serious side effects. Some individuals might feel slight discomfort or tingling during the treatment, but these sensations are usually mild and resolve quickly.

A review of clinical studies reported no serious problems, suggesting that the therapy is safe for most people. This treatment is gaining popularity in the U.S. and is available from many healthcare providers, further supporting its safety.

Although the FDA has not specifically approved the therapy for erectile dysfunction, the lack of serious side effects in the reviewed studies suggests it is a safe option for those considering this treatment.12345

Why are researchers excited about this trial?

Unlike the standard treatments for erectile dysfunction, such as oral medications like Viagra or Cialis, low-intensity acoustic shockwave therapy offers a non-invasive approach that directly targets the problem. This therapy uses sound waves to improve blood flow to the penis, potentially restoring natural erectile function without the need for pills or injections. Researchers are excited because it represents a novel method that could provide long-term benefits and address the root cause of erectile dysfunction rather than just its symptoms.

What evidence suggests that this shockwave therapy is effective for erectile dysfunction?

Research has shown that low-intensity sound wave therapy, which participants in this trial will receive, can help men with erectile dysfunction (ED) by improving blood flow to the penis, potentially restoring sexual function. A review of several studies found that men who received this treatment reported better erectile function, regardless of the severity of their ED. More people in the U.S. are trying this therapy, although some remain unsure about it. Overall, current evidence suggests it could be a promising option for those with ED.14678

Are You a Good Fit for This Trial?

This trial is for sexually active men aged 18-64 with erectile dysfunction who have shown increased penile firmness on elastography. Participants must consent to the study's procedures and be available throughout its duration. Men using erectogenic medications, those with penile implants, cardiac devices, or sensitive to electromagnetic radiation are excluded.

Inclusion Criteria

I am a man with erectile dysfunction and my tests show increased firmness.
Stated willingness to comply with all study procedures and availability for the duration of the study
Provision of signed and dated informed consent form
See 1 more

Exclusion Criteria

My ultrasound showed signs of testicular cancer.
My prostate cancer has not been treated.
Patients who are using devices which are sensitive to electromagnetic radiation
See 5 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive Low-Intensity Shockwave Therapy (LiST) to improve penile blood flow and restore sexual function

12 weeks
8 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Low-intensity acoustic shockwave therapy
Trial Overview The study tests whether Low-Intensity Shockwave Therapy (LiST) can alter the increased corporal firmness associated with erectile dysfunction. This pilot study will treat participants found to have this condition through standard evaluations.
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: Low Intensity Acoustic Shockwave TherapyExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Northwell Health

Lead Sponsor

Trials
481
Recruited
470,000+

Citations

Effectiveness of Low-Intensity Extracorporeal Shock Wave ...Thus, subjective results suggest that shock waves could enhance erectile function in patients with ED, regardless of the severity of the dysfunction. Penile ...
Low-intensity extracorporeal shock wave therapy for ...To review the evidence of clinical efficacy of low-intensity extracorporeal shock wave therapy (Li-ESWT) for the treatment of erectile dysfunction (ED).
Extracorporeal shock wave therapy for erectile dysfunctionExtracorporeal shock wave therapy (ESWT) for erectile dysfunction (ED) presents a challenging paradox. While numerous clinical studies, systematic reviews, and ...
Shockwave Therapy for Erectile Dysfunction Gaining in ...Off-label use of low-intensity extracorporeal shockwave therapy for treating erectile dysfunction (ED) is growing in popularity in the United States.
Low-intensity Extracorporeal Shock Wave Treatment ...We reviewed 14 studies of men who received low-intensity extracorporeal shock wave treatment (LI-ESWT) for erectile dysfunction (ED). There was evidence that ...
Safety and efficacy of low intensity shockwave (LISW ...Erectile dysfunction (ED) is the main complaint in male sexual medicine and is defined as the persistent inability to attain and maintain an erection sufficient ...
Shockwave Therapy: Erectile Dysfunction (ED) TreatmentRecently, urologists have begun using this therapy to treat erectile dysfunction (ED). University of Utah Health offers shockwave therapy as an option for ...
Low Intensity Shockwave Therapy for Erectile DysfunctionIt is estimated that about 1 in 10 adult males suffer from erectile dysfunction (ED) on a long-term basis. ... Is low-intensity shockwave therapy for erectile ...
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