Aspirin for Ankle Fracture Healing
What You Need to Know Before You Apply
What is the purpose of this trial?
This study aims to identify if postoperative aspirin use leads to a delay in fracture healing. NSAIDs have long been avoided in the management of fractures, due to the belief that they may impair fracture healing. As aspirin is frequently prescribed for long-term management of various medical conditions, it is worth understanding if continuing to take aspirin during the process of fracture healing has a clinically significant effect on the rate of fracture healing.
Are You a Good Fit for This Trial?
Adults over 18 with a recent ankle fracture requiring surgery can join this trial. They must be healthy enough for orthopedic surgery and able to consent. Excluded are those with multiple fractures, aspirin allergies, bleeding disorders, or on blood thinners.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo surgical repair of ankle fractures and are randomized to receive or not receive aspirin postoperatively
Follow-up
Participants are monitored for fracture healing and functional outcomes with follow-up appointments at 2 weeks, 6 weeks, 3 months, 6 months, and 1 year
What Are the Treatments Tested in This Trial?
Interventions
- Aspirin
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Alabama at Birmingham
Lead Sponsor