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Radiation Therapy

SBRT for Prostate Cancer

N/A

Waitlist Available

Research Sponsored by Hoag Memorial Hospital Presbyterian

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Clinical stage T1-3 (AJCC 7th edition).

Males age ≥ 18

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 5 years

Awards & highlights

Study Summary

This trial will compare the long term efficacy and side effects of SBRT done with the Elekta Versa or Agility System versus the standard EBRT.

Who is the study for?

This trial is for men over 18 with early to moderately advanced prostate cancer (stage T1-3) who haven't had previous treatments like surgery, cryosurgery, or radiation. They must be able to consent and fill out a quality of life questionnaire. Men with distant metastases, lymph node involvement, severe bowel disease, or prior chemotherapy are excluded.Check my eligibility

What is being tested?

The study tests the effectiveness and side effects of Stereotactic Body Radiation Therapy (SBRT) using Elekta Versa or Agility Systems in treating prostate cancer. SBRT is an advanced technique delivering targeted radiation in fewer sessions compared to traditional therapy—5 versus 42-45 treatments.See study design

What are the potential side effects?

Potential side effects include typical reactions from radiation such as skin irritation near the treatment area, fatigue, urinary issues like increased frequency or discomfort during urination, bowel changes including diarrhea or rectal discomfort.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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My cancer is in an early to mid-stage, not the most advanced.

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I am a man aged 18 or older.

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My prostate cancer diagnosis was confirmed through a tissue examination.

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My prostate biopsy was analyzed and given a Gleason score.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 5 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~5 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and 5 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Malignant neoplasm of prostate

Secondary outcome measures

The secondary aim is to obtain quality of life data to examine the potential complications associated with SBRT: detailed symptom questionnaire

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Agility SystemsExperimental Treatment1 Intervention

This study seeks to investigate biochemical failure rates for patients treated with SBRT utilizing Agility Systems, as well as obtain quality of life data and assess the intrafraction motion in approximately 15 patients for 5 years following SBRT.

Group II: Elekta Versa HDActive Control1 Intervention

This study seeks to investigate biochemical failure rates for patients treated with SBRT utilizing Elekta machines, as well as obtain quality of life data and assess the intrafraction motion in approximately 15 patients for 5 years following SBRT.

0 / 4Eligibility criteria met

Find a Location

Who is running the clinical trial?

Hoag Memorial Hospital PresbyterianLead Sponsor

34 Previous Clinical Trials

14,595 Total Patients Enrolled

1 Trials studying Prostate Cancer

184 Patients Enrolled for Prostate Cancer

Media Library

Stereotactic Body Radiation Therapy (SBRT) for Prostate Cancer (Radiation Therapy) Clinical Trial Eligibility Overview. Trial Name: NCT03889119 — N/A

Prostate Cancer Research Study Groups: Agility Systems, Elekta Versa HD

Prostate Cancer Clinical Trial 2023: Stereotactic Body Radiation Therapy (SBRT) for Prostate Cancer Highlights & Side Effects. Trial Name: NCT03889119 — N/A

Stereotactic Body Radiation Therapy (SBRT) for Prostate Cancer (Radiation Therapy) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03889119 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Have any new participants been welcomed into this research endeavor recently?

"According to the clinicaltrials.gov website, this study has not been actively recruiting since March 14th 2022. Although recruitment for this trial is currently paused, there are 1,322 other medical trials looking for volunteers right now."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Stereotactic Body Radiation Therapy (SBRT) for Prostate Cancer

Kevin Lin 2016. "Stereotactic Body Radiation Therapy (SBRT) for Prostate Cancer". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03889119.

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