Relay Pro Stent-Graft for Aortic Dissection
This study is evaluating whether a new type of stent may help treat aortic dissection.
See full descriptionAbout the trial for Aortic Dissection
Treatment Groups
This trial involves 2 different treatments. Relay Pro Stent-Graft is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
Eligibility
This trial is for patients born any sex aged 18 and older. There are 10 eligibility criteria to participate in this trial as listed below.
Approximate Timelines
Measurement Requirements
This trial is evaluating whether Relay Pro Stent-Graft will improve 1 primary outcome and 3 secondary outcomes in patients with Aortic Dissection. Measurement will happen over the course of 30 days.
Patient Q & A Section
What are the signs of aortic dissection?
This is a very uncommon presentation and its clinical and radiological features are similar to aortic dissection. Early detection of this disorder can prevent serious complications and mortality.
Can aortic dissection be cured?
The mortality of the group diagnosed with aortic dissection after 1 year was 50%, and after 2 years was 87%. The survival of the individuals with aortic dissection was good but there was a high mortality even after the operation.
How many people get aortic dissection a year in the United States?
Only 50,000-100,000 per year are diagnosed with aortic dissection. The actual number of people being treated or killed is probably much higher. Most deaths from ruptured aorta occur in the infrarenal aorta and not the aorta proper.
What causes aortic dissection?
Patients with symptomatic aortic dissection present with the classic signs and symptoms of aortitis, including dissection. Dissection must be ruled out before surgical treatment is considered. The risk of surgical intervention is low, and most dissections can be managed by observation. Asymptomatic dissections are typically diagnosed based on signs and symptoms, regardless of aortitis status. Patients with asymptomatic dissections are less likely to undergo surgical intervention.
What are common treatments for aortic dissection?
Acute treatment for acute aortic dissection is surgical repair of the aortic dissection. It is essential to obtain prompt surgical repair of acute aortic dissection.
What is aortic dissection?
Aortic dissections are rare in children. The most common types in children are idiopathic and traumatic. Older children are more likely to present with dissection in the ascending, rather than in the aortic arch. As compared with older children, younger children are at lower risk of having a thoracic aortic dissection due to their greater proportion of body weight in the left sided thorax. Thoracic aortic dissection was more common in girls, had an earlier age of onset, and had a higher incidence of cardiac disease than a trisectoral aortic dissection. Aortic dissection was most common in the left anterior descending artery.
What is relay pro stent-graft?
In patients with coexistent renal insufficiency, pre-procedural creatinine clearance had significant influence on the long-term clinical outcome of AVEG, and these results should be taken into consideration in patient selection for this procedure.
What are the common side effects of relay pro stent-graft?
Relay PS-G can be performed on both sides. If there are no serious complications, it can be performed successfully on both the left side and the right atrial side with satisfactory results.
Does aortic dissection run in families?
A high percentage of aortic dissection presenting as Marfan syndrome is estimated to be genetically linked. Heterozygous mutation detection rates of AS are estimated to be similar to those reported for autosomal recessive mutations or even greater as suggested by the higher mutation frequencies of AS. This is based on heterozygotes frequency estimates from published studies and indicates that AS may be underdiagnosed in some families.
Have there been any new discoveries for treating aortic dissection?
There have been some recent breakthroughs in our understanding of the pathophysiology of aortic dissection, which has helped in providing treatments that are potentially effective in reducing morbidity and mortality. The identification of a new target for pharmacotherapy is important for those with aortic dissection because current treatment options are not ideal.
What is the average age someone gets aortic dissection?
Onset can occur at any age. The average age is 57 years. The male-to-female ratio is 1:1.3. There is an association between aortic dissection and congenital disorders. This is because the risk of developing the dissection is increased by the mutation of those genes.
Who should consider clinical trials for aortic dissection?
Patients should consider clinical trials for AVAD. Patients can benefit from such trials by gaining knowledge of the risk profiles, disease processes, and treatment options. Clinical trials can help refine the management and treatment of patients to help reduce mortality, morbidity, and complications associated with the disease.