Study Summary
This trial will assess if ABBV-154 is a safe and effective treatment for PMR in adults aged 50 years or older.
- Polymyalgia Rheumatica
Video Summary
Treatment Effectiveness
Phase-Based Effectiveness
Study Objectives
1 Primary · 3 Secondary · Reporting Duration: Up to Week 52
Trial Safety
Phase-Based Safety
Trial Design
4 Treatment Groups
ABBV-154 Dose A
1 of 4
ABBV-154 Dose B
1 of 4
ABBV-154 Dose C
1 of 4
Placebo
1 of 4
Experimental Treatment
Non-Treatment Group
181 Total Participants · 4 Treatment Groups
Primary Treatment: ABBV-154 · Has Placebo Group · Phase 2
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 50 - 80 · All Participants · 2 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Who else is applying?
What state do they live in?
| Illinois | 50.0% |
| California | 50.0% |
How old are they?
| 65+ | 100.0% |
What portion of applicants met pre-screening criteria?
| Met criteria | 50.0% |
| Did not meet criteria | 50.0% |
What site did they apply to?
| Springfield Clinic /ID# 228840 | 100.0% |
Frequently Asked Questions
What is the aggregate amount of participants in this research?
"This clinical trial necessitates 160 eligible patients. Patient enrollment locations include The Waterside Clinic /ID# 230364 in Barrie, Ontario and Rheumatology Care Center PLLC /ID# 232306 in Bellaire, Texas." - Anonymous Online Contributor
Has the FDA granted authorization to ABBV-154?
"Our team has rated ABBV-154's safety as a 2 due to the lack of clinical evidence for its efficacy, though there is some data indicating it may be safe." - Anonymous Online Contributor
Are there any areas in North America where this clinical trial is currently being implemented?
"The Waterside Clinic (ID# 230364) in Barrie, Ontario; Rheumatology Care Center PLLC (ID# 232306) in Bellaire, Texas; and St Jude Heritage Medical Group (ID# 228681) in Fullerton, California are among the 38 sites that have been enlisted to partake in this study." - Anonymous Online Contributor
Are fresh participants being admitted to this trial presently?
"Affirmative. Data published on clinicaltrials.gov reveals that this medical trial, which started in September 9th 2021 is actively recruiting patients. Approximately 160 participants must be enrolled from 35 different sites." - Anonymous Online Contributor
Is enrollment open to geriatric individuals for this investigation?
"Elderly individuals aged between 50 and 80 years old have the opportunity to be enrolled in this scientific research." - Anonymous Online Contributor
What criteria must one fulfill to be eligible for enrollment in this experiment?
"This clinical trial is seeking 160 individuals with a diagnosis of Polymyalgia Rheumatica, aged between 50 and 80. Principal eligibility requirements include: conforming to the 2012 EULAR/ACR provisional classification criteria for PMR; having experienced two unequivocal episodes of PMR flare-up; being on a consistent dose of prednisone; and adhering to the protocol's tapering regimen concerning glucocorticoids." - Anonymous Online Contributor