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Monoclonal Antibodies

ANX005 for Autoimmune Hemolytic Anemia

Phase 2
Waitlist Available
Led By Morie Gertz, MD
Research Sponsored by Annexon, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Screening 3 weeks
Treatment Varies
Follow Up up to day 71
Awards & highlights

Study Summary

This trial will test a new drug, ANX005, for people with Warm Autoimmune Hemolytic Anemia. They will evaluate how safe and tolerable the drug is.

Eligible Conditions
  • Warm Autoimmune Hemolytic Anemia


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to day 71
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to day 71 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in disease activity biomarkers
Safety: Treatment-emergent adverse events (TEAEs)
Secondary outcome measures
Change in complement system biomarkers
Plasma concentrations

Trial Design

1Treatment groups
Experimental Treatment
Group I: ANX005Experimental Treatment1 Intervention
Participants will receive two once-weekly doses of ANX005 at specific time points
First Studied
Drug Approval Stage
How many patients have taken this drug
Completed Phase 2

Find a Location

Who is running the clinical trial?

Annexon, Inc.Lead Sponsor
12 Previous Clinical Trials
792 Total Patients Enrolled
Morie Gertz, MDPrincipal InvestigatorMayo Clinic, Rochester, MN
Study DirectorStudy DirectorAnnexon, Inc.
1,208 Previous Clinical Trials
489,689 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is ANX005 reported to be risk-free for individuals?

"The safety rating for ANX005 was determined to be 2 out of 3, given the lack of evidence confirming its efficacy from Phase 2 trials."

Answered by AI

Are there any vacancies to partake in this investigation?

"Based on the information found at clinicaltrials.gov, this study is accepting applicants and was initially posted in November 2021 with updates occurring as recently as June 2022."

Answered by AI

How many enrollees are currently partaking in this scientific investigation?

"Affirmative. The clinical trial records located on clinicaltrials.gov attest that this particular study was first posted in November 10th 2021 and modified last June 21st 2022 looking for 12 patient volunteers from a single medical centre."

Answered by AI
~2 spots leftby Apr 2025