Treatment for Written Exposure Therapy

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Prevail Health Inc., Chicago, IL
Written Exposure Therapy+1 More
Eligibility
18+
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether an online therapy program may help reduce symptoms of post-traumatic stress disorder.

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Eligible Conditions

  • Written Exposure Therapy
  • Imaginal Exposure Therapy

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

This trial is evaluating whether Treatment will improve 1 primary outcome and 3 secondary outcomes in patients with Written Exposure Therapy. Measurement will happen over the course of Change in total score from baseline to 3-months post treatment (approximately 14-18 weeks)..

Week 18
Brief version of the difficulties in emotion regulation scale (DERS-16; Bjureberg et al,. 2016)
Patient Health Questionnaire-9 (PHQ-9; Kroenke, Spitzer, & Williams, 2001).
Post Traumatic Stress Disorder CheckList for Diagnostic and Statistical Manual - 5 (PCL-5; Weathers, et al., 2013)
Work and Social Adjustment Scale (WSAS; Mundt et al., 2002)

Trial Safety

Trial Design

2 Treatment Groups

Imaginal Exposure Therapy
1 of 2
Written Exposure Therapy
1 of 2
Active Control

This trial requires 350 total participants across 2 different treatment groups

This trial involves 2 different treatments. Treatment is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Imaginal Exposure Therapy
Behavioral
Imaginal exposure therapy will involve verbal recounting of trauma memories for 30 minutes with therapist instruction and feedback before and after each recounting exercise.
Written Exposure Therapy
Behavioral
Written exposure therapy (Sloan et al., 2012) is a brief evidence-based treatment for PTSD (US Dept. of VA & DoD, 2017), wherein patients are asked to write about their trauma memories for 30 minutes, with therapist instruction and feedback before and after each writing exercise.

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: change in total score from baseline to 3-months post treatment (approximately 14-18 weeks).
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly change in total score from baseline to 3-months post treatment (approximately 14-18 weeks). for reporting.

Who is running the study

Principal Investigator
C. M.
Carmen McLean, Principal Investigator
Palo Alto Veterans Institute for Research

Closest Location

Prevail Health Inc. - Chicago, IL

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 3 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Able to read/write English
Internet connection allowing stable access to the Vets Prevail website
A clinically significant PCL-5 score of 31 or above.

Patient Q&A Section

What is written exposure therapy?

"Exposure therapy is an effective treatment for PTSD, OCD, alcohol and drug abuse, and gambling disorder. It has also been found to be effective in reducing the desire to smoke, but its effect in reducing the desire to smoke among substance abusers remains unclear. Exposure therapy often involves the use of an explicit written treatment manual that encourages clients to write their own stories about their traumatic experiences. This is sometimes referred to as "imaginal exposure". In an 8-week randomized control study, written exposure therapy helped post-traumatic stress disorder (PTSD) clients who experienced traumatic life events such as war, rape or childhood abuse to reduce symptoms of PTSD after exposure to the events in the written treatment manual." - Anonymous Online Contributor

Unverified Answer

What are the signs of written exposure therapy?

"Results of this study suggest that in a majority of cases, WRATE is effective in the treatment of PTSD, anxiety, and bulimia nervosa. In these conditions, WRATE is effective in reducing symptoms, and may be helpful in improving the health of sufferers. Data from a recent study support theoretical assumptions, supported by empirical findings, that WRATE may influence emotional change by a variety of psychological mechanisms, the mechanisms of which remain to be determined. Additional research is needed, however, in order to evaluate the contribution of specific mechanisms to treatment outcomes." - Anonymous Online Contributor

Unverified Answer

What causes written exposure therapy?

"The current findings offer novel perspectives and support the relevance of E-learning. In this way, the results of the study contribute towards the further application of exposure theory." - Anonymous Online Contributor

Unverified Answer

What are common treatments for written exposure therapy?

"Some individuals with written exposure therapy may achieve greater improvement in a variety of symptoms by using their own written text to create stressful situations. In a recent study, findings demonstrate the efficacy of this technique and suggest that written exposure therapy may be a useful tool in the treatment of a variety of anxiety and somatoform disorders." - Anonymous Online Contributor

Unverified Answer

How many people get written exposure therapy a year in the United States?

"A relatively small percentage of patients with BDD receive treatment, with the vast majority treated with supportive care. The proportion of patients who responded to WET declined only slightly in a 10-year period. Although WET has an important role in the treatment of BDD, the proportion of patients who received more than 150 WET sessions was only slightly increased." - Anonymous Online Contributor

Unverified Answer

Can written exposure therapy be cured?

"We conclude that written self-directed exposure therapy is an established treatment for PTSD. However, written exposure therapy has been shown to be ineffective, at least in short-term research settings. For longer term self-directed treatment, a large-scale multi-center randomized trial is probably needed." - Anonymous Online Contributor

Unverified Answer

What is treatment?

"There is ample and effective evidence in both psychotherapy and writing to support treatments that are effective in controlling OCD. However, there is currently no evidence that any particular treatment is more effective than any other. Patients in both control, writing and writing + speech-therapy groups reported the benefits of treatment at baseline, and outcomes were not different between treatment groups." - Anonymous Online Contributor

Unverified Answer

What is the average age someone gets written exposure therapy?

"Approximately 40.3% of study participants had finished treatment by age 46. There is no data comparing older vs younger patients receiving written exposure therapy. Recent findings provides valuable insight into what an average person with PTSD might be faced with. The authors suggest more research be implemented to better understand and understand the average age of people receiving written exposure therapy before writing exposure therapy should be discontinued." - Anonymous Online Contributor

Unverified Answer

What are the latest developments in treatment for therapeutic use?

"[Cognitive behavioral therapy and psychoeducation have been validated and proven to be effective for treating eating disorders, though there are few studies in the field of weight management. The most recent developments in treatment are focused on integrating behavior therapy with an electronic medium. One is behavioral weight loss, which has proven to be a beneficial treatment approach to many patients struggling with obesity. The use of computers and mobile devices to support and improve mental flexibility is another latest development in treatment.-Liz Kao] answer: These studies have demonstrated the effectiveness of many types of weight loss treatments. These include [fasig–lean method (in the clinic), diet plus exercise treatment, diet alone treatment, and [metronomic therapy] (in the clinic)]." - Anonymous Online Contributor

Unverified Answer

What does treatment usually treat?

"Treatment of depression in children is currently based largely on clinical trials. However, even these trials have significant limitations and the evidence base for treatment effect of psychotherapy as a stand-alone treatment for depression in children is very limited. There is a need to develop new treatment approaches. The first step would be the use of more sensitive diagnostic tests and biomarkers of pediatric depression to develop and evaluate new treatments. These studies could also contribute to the development and modification of existing treatments." - Anonymous Online Contributor

Unverified Answer

Have there been other clinical trials involving treatment?

"Current clinical trials for SZ are limited to small case populations with relatively poor participation, but they may be representative of SZ as encountered in clinical practice." - Anonymous Online Contributor

Unverified Answer

Has treatment proven to be more effective than a placebo?

"Findings from a recent study suggests that the addition of WR in the context of ER counseling to a brief cognitive therapy intervention is not more effective in improving change in psychological distress compared to the control condition. The fact that this intervention did work has the potential to make the practice of brief cognitive therapy a potentially useful addition to counseling. Further research should explore the potential value of this adjunct." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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