← Back to Search

Melanocortin receptor agonist

Afamelanotide for Vitiligo

Phase 2
Recruiting
Research Sponsored by Clinuvel, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up from baseline to day 168
Awards & highlights

Summary

This trialwill test a drug to help restore skin color in people with vitiligo on the face and body.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~from baseline to day 168
This trial's timeline: 3 weeks for screening, Varies for treatment, and from baseline to day 168 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Proportion of participants achieving Vitiligo Area Scoring Index (VASI)25 on facial lesions
Secondary outcome measures
Change in Noticeability of Vitiligo using a vitiligo validated specific tool (B)
Change in Perception of Vitiligo Severity using a vitiligo validated specific tool (A)
Change in Quality of life using a vitiligo specific tool (C)
+3 more

Side effects data

From 2009 Phase 3 trial • 100 Patients • NCT04053270
45%
Headache
34%
Nausea
17%
Nasopharyngitis
13%
Diarrhoea
13%
Influenza
12%
Dizziness
12%
Fatigue
11%
Back pain
9%
Abdominal pain
8%
Implant site haematoma
8%
Vomiting
8%
Implant site pain
8%
Flushing
7%
Abdominal pain upper
7%
Upper respiratory tract infection
7%
Pyrexia
7%
Migraine
7%
Haematoma
5%
Oedema peripheral
5%
Cough
4%
Toothache
4%
Oropharyngeal pain
1%
Spinal fracture
1%
Thrombocytopenia
1%
Cholelithiasis
1%
Dysmenorrhoea
100%
80%
60%
40%
20%
0%
Study treatment Arm
Afamelanotide
Placebo

Trial Design

1Treatment groups
Experimental Treatment
Group I: AfamelanotideExperimental Treatment1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Afamelanotide
2014
Completed Phase 3
~520

Find a Location

Who is running the clinical trial?

Clinuvel, Inc.Lead Sponsor
1 Previous Clinical Trials
200 Total Patients Enrolled
1 Trials studying Vitiligo
200 Patients Enrolled for Vitiligo
~2 spots leftby Jul 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top