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Stem Cell Therapy

hematopoietic stem cell infusion for Hunter Syndrome

Phase 1 & 2
Waitlist Available
Research Sponsored by Talaris Therapeutics Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up one month to three years
Awards & highlights

Study Summary

This trial is testing a new way to give stem cell transplants that may help prevent GVHD while still being effective.

Eligible Conditions
  • Hunter Syndrome
  • Hurler Syndrome
  • Alpha-Mannosidosis
  • Hurler-Scheie Syndrome
  • Sandhoff Disease
  • Sanfilippo Syndrome
  • Krabbe Disease
  • Metachromatic Leukodystrophy
  • Niemann-Pick Disease
  • Adrenoleukodystrophy
  • Tay-Sachs Disease
  • Pelizaeus-Merzbacher Disease

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~one month to three years
This trial's timeline: 3 weeks for screening, Varies for treatment, and one month to three years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Production of missing enzyme at levels greater than or equal to 10% of normal
Secondary outcome measures
Enriched Hematopoetic Stem Cell Engraftment

Trial Design

1Treatment groups
Experimental Treatment
Group I: Inherited Metabolic Disorder PatientsExperimental Treatment1 Intervention
Recipients are treated with hematopoietic stem cell infusion from living donors

Find a Location

Who is running the clinical trial?

Talaris Therapeutics Inc.Lead Sponsor
11 Previous Clinical Trials
99 Total Patients Enrolled
Duke UniversityOTHER
2,358 Previous Clinical Trials
3,420,066 Total Patients Enrolled
1 Trials studying Hunter Syndrome
25 Patients Enrolled for Hunter Syndrome
Suzanne T Ildstad, MDStudy DirectorTalaris Therapeutics Inc.
6 Previous Clinical Trials
100 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any opportunities for individuals to participate in this medical trial presently?

"Not presently. Clinicaltrials.gov indicates that this experiment, which was first posted April 1st 2011 and amended July 15th 2022, is not taking on participants at the moment; however there are a host of other clinical trials actively enrolling patients right now.."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Phase I/II Pilot Study of Mixed Chimerism to Treat Inherited Metabolic Disorders
2011. "Phase I/II Pilot Study of Mixed Chimerism to Treat Inherited Metabolic Disorders". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01372228.
~0 spots leftby Apr 2025
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